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Table 2 Direction of the concordance/discordance in the expression of ER, PR and HER2

From: Comparison of the HER2, estrogen and progesterone receptor expression profile of primary tumor, metastases and circulating tumor cells in metastatic breast cancer patients

a) ER

 

Tumor ER-

Tumor ER+

 

AdnaTest ER-

10

21

 

AdnaTest ER+

1

4

  

Fishers exact Test: p = 0,51

  

Metastases ER-

Metastases ER+

 

AdnaTest ER-

10

20

 

AdnaTest ER+

0

5

  

Fishers exact Test: p = 0,16

  

Metastases ER-

Metastases ER+

 

Tumor ER-

9

19

 

Tumor ER+

1

2

  

Fishers exact Test: p = 7,2E-6

b) PR

 

Tumor PR-

Tumor PR+

 

AdnaTest PR-

14

19

 

AdnaTest PR+

1

2

  

Fishers exact Test: p = 0,62

  

Metastases PR-

Metastases PR+

 

AdnaTest PR-

14

18

 

AdnaTest PR+

1

2

  

Fishers exact Test: p = 0,60

  

Metastases PR-

Metastases PR+

 

Tumor PR-

13

2

 

Tumor PR+

2

18

  

Fishers exact Test: p = 6,23E-6

c)HER2

 

Tumor HER2-

Tumor HER2+

 

AdnaTest HER2-

12

6

 

AdnaTest HER2+

8

8

  

Fishers exact Test: p = 0,043

  

Metastases HER2-

Metastases HER2+

 

AdnaTest HER2-

14

4

 

AdnaTest HER2+

8

10

  

Fishers exact Test: p = 0,043

  

Metastases HER2-

Metastases HER2+

 

Tumor HER2-

17

3

 

Tumor HER2+

4

10

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BMC Cancer

ISSN: 1471-2407

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