Fig. 2

Effects of test compounds on cell cycle progression. a Non-small cell lung cancer (NSCLC) cells cultured in the presence of test compounds (C1–C2) at 10 μM for 24–48 h were harvested, and then cell cycle profiles were analyzed. Representative histograms of three different experiments are shown. b NSCLC cells cultured in the presence of test compounds (C1–C5) at 10 μM for 24–48 h were harvested, and then cell cycle profiles were analyzed. Fractions of G2/M at 24 h in NSCLC cells (A549, LU99, EBC-1, and H1299 cells) [left panel] and G1 at 48 h in A549 and H1299 cells [light panel] are shown. Data are presented as mean ± SE of 3 independent experiments. * and ** indicate p < 0.05 and p < 0.01 compared with dimethyl sulfoxide control, respectively