Fig. 2

PAC triggers apoptosis more efficiently in ERα-negative than in ERα-positive breast cancer cells. Cells were either sham-treated or challenged with PAC (10 μM) for 72 h, and then cell death was assessed by annexin V/PI in association with flow cytometry. a Charts. b Histogram showing the proportion of cell death (apoptosis + necrosis) in each cell line. Error bars represent means ± SD from three different experiments, *, P ≤ 0.05