Table 6 The results of univariate and multivariate analyses of the expression of Sema4D and PlexinB1, clinicopathological findings and relapse-free survival in the patients with colorectal cancer

Gender

0.966

0.598–1.617

0.966

 Male vs. Female

Age

1.508

0.922–2.473

0.106

 ≧70 vs. <70

Histology

2.845

1.480–5.081

0.002

1.743

0.894–3.178

0.099

 Other vs. well/mod

Depth of tumor invasion

4.062

1.985–9.781

<0.001

2.12

0.911–5.824

0.083

 T3/T4 vs.T1/T2

Lymph node metastasis

4.871

2.729–9.358

<0.001

2.783

1.425–5.822

0.002

 Positive vs. negative

Lymphatic invasion

3.848

2.001–8.344

<0.001

1.658

0.740–4.129

0.227

 Positive vs. negative

Venus invasion

2.183

1.217–3.729

0.01

1.049

0.569–1.856

0.873

 Positive vs. negative

Sema4D and PlexinB1 expression

2.647

1.611–4.326

<0.001

1.079

1.013–2.868

0.044

 Both positive vs. others