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Table 6 The results of univariate and multivariate analyses of the expression of Sema4D and PlexinB1, clinicopathological findings and relapse-free survival in the patients with colorectal cancer

From: The combined expression of Semaphorin4D and PlexinB1 predicts disease recurrence in colorectal cancer

  Univariate analysis Multivariate analysis
Variables Hazard ratio 95 % CI p value Hazard ratio 95 % CI p value
Gender 0.966 0.598–1.617 0.966    
 Male vs. Female    
Age 1.508 0.922–2.473 0.106    
70 vs. <70    
Histology 2.845 1.480–5.081 0.002 1.743 0.894–3.178 0.099
 Other vs. well/mod    
Depth of tumor invasion 4.062 1.985–9.781 <0.001 2.12 0.911–5.824 0.083
 T3/T4 vs.T1/T2    
Lymph node metastasis 4.871 2.729–9.358 <0.001 2.783 1.425–5.822 0.002
 Positive vs. negative    
Lymphatic invasion 3.848 2.001–8.344 <0.001 1.658 0.740–4.129 0.227
 Positive vs. negative      
Venus invasion 2.183 1.217–3.729 0.01 1.049 0.569–1.856 0.873
 Positive vs. negative    
Sema4D and PlexinB1 expression 2.647 1.611–4.326 <0.001 1.079 1.013–2.868 0.044
 Both positive vs. others    
  1. Sema4D semaphorin 4D. Other poorly-differnetiated, mucinous-type, small-cell, signet-cell. CI confidence interval