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Table 5 The results of univariate and multivariate analyses of the expression of Sema4D and PlexinB1, clinicopathological findings and overall survival in the patients with colorectal cancer

From: The combined expression of Semaphorin4D and PlexinB1 predicts disease recurrence in colorectal cancer

  Univariate analysis Multivariate analysis
Variables Hazard ratio 95 % CI p value Hazard ratio 95 % CI p value
Gender 0.928 0.574–1.509 0.762    
 Male vs. Female    
Age 1.365 0.841–2.207 0.205    
70 vs. <70    
Histology 2.666 1.391–4.373 0.004 1.758 0.901–3.205 0.094
 Other vs. well/mod    
Depth of tumor invasion 4.574 2.032–13.08 <0.001 2.692 1.022–9.317 0.044
 T3/T4 vs.T1/T2    
Lymph node metastasis 4.469 2.432–9.017 <0.001 2.304 1.138–5.069 0.019
 Positive vs. negative    
Lymphatic invasion 3.108 1.622–6.725 <0.001 1.318 0.603–3.235 0.505
 Positive vs. negative      
Venus invasion 2.6 1.554–4.25 <0.001 1.409 0.813–2.394 0.216
 Positive vs. negative    
Sema4D and PlexinB1 expression 2.567 1.587–4.158 <0.001 1.681 1.004–2.819 0.047
 Both positive vs. others    
  1. Sema4D semaphorin 4D. Other poorly-differnetiated, mucinous-type, small-cell, signet-cell. CI confidence interval