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Table 1 Correlations between clinicopathological findings and the expression of Sema4D and PlexinB1

From: The combined expression of Semaphorin4D and PlexinB1 predicts disease recurrence in colorectal cancer

Variables Sema4D expression p value PlexinB1 expression p value
Positive Negative Positive Negative
(n = 95) (n = 131) (n = 105) (n = 121)
Age (years)       
 Mean ± SD 65.2 ± 12.3 67.2 ± 10.5 0.426 67.6 ± 11.0 65.8 ± 11.5 0.23
Gender       
 Male 51(53.7) 73(55.7) 0.76 56(53.3) 68 0.666
 Female 44(46.3) 58(44.3) 49(46.7) 53
Stage       
 I 15(15.8) 43(32.8) 0.001 16(15.2) 42 <0.001
 II 21(22.1) 36(27.5) 19(18.1) 38
 III 59(62.1) 52(36.7)   70(66.7) 41  
Histology       
 Well/mod 82(86.3) 120(91.6) 0.206 91 111 0.217
 Other 13(13.7) 11(8.4) 14 10
Depth of tumor invasion       
 T1/T2 18(18.9) 50(38.2) 0.001 20 48 0.006
 T3/T4 77(81.1) 81(61.8) 85 73
Lymph node metastasis       
 negative 37(38.9) 78(59.5) 0.001 35 79 <0.001
 positive 58(61.1) 53(40.5) 69 42
Lymphatic invasion       
 Negative 18(18.9) 66(50.4) <0.001 21 57 <0.001
 Positive 77(81.1) 65(49.6) 84 64
Venus invasion       
 Negative 70(73.7) 117(89.3) <0.001 76 111 <0.001
 Positive 25(26.3) 14(10.7) 29 10
  1. Sema4D semaphorin 4D. Other poorly-differnetiated, mucinous-type, small-cell, signet-cell