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Table 1 Clinicopathological characteristics of the participating patients

From: Predictive value of vrk 1 and 2 for rectal adenocarcinoma response to neoadjuvant chemoradiation therapy: a retrospective observational cohort study

Variables (N = 67)  
Age, years, median (IQR) 72 (63; 77)
Gender  
 Male 43 (64.2 %)
 Female 24 (35.8 %)
ECOG performance status  
 0 38 (56.7 %)
  ≥ 1 29 (43.3 %)
Tumor invasion depth  
 T1 1 (1.5 %)
 T2 9 (13.4 %)
 T3 53 (79.1 %)
 T4 4 (6 %)
Lymph node metastases  
 N0 13 (19.4 %)
 N+ 54 (80.6 %)
Grade of differentiation (N = 60)  
 Low grade 17 (28.3 %)
 Moderate-High grade 43 (71.7 %)
LVI (N = 63)  
 Yes 6 (9.5 %)
 No 57 (90.4 %)
Tumor size, cm, median (IQR) 5 (4; 6)
Anal verge distance, cm, median (IQR) 8 (5; 10)
Neoadjuvant chemoradiotherapy  
 RDT- Flouropyrimidines 54 (80.6 %)
 RDT- Flouropyrimidines - Oxaliplatin 13 (19.4 %)
T downstaging  
 Yes 36 (53.7 %)
 No 31 (46.3 %)
Tumor Regression Grading  
 TRG 0 - 1 31 (46.3 %)
 TRG 2 - 3 36 (53.7 %)
Responder  
 Yes 45 (67.2 %)
 No 22 (32.8 %)
  1. Abbreviations: ECOG Eastern Cooperative Oncology Group, RDT radiotherapy, TRG tumor regression grading, LVI lymphovascular invasion, IQR Interquartile Range, reported as quartile 1st and 3th, respectively