Table 1 Clinicopathological characteristics of the participating patients
Variables (N = 67) | |
|---|---|
Age, years, median (IQR) | 72 (63; 77) |
Gender | |
Male | 43 (64.2 %) |
Female | 24 (35.8 %) |
ECOG performance status | |
0 | 38 (56.7 %) |
≥ 1 | 29 (43.3 %) |
Tumor invasion depth | |
T1 | 1 (1.5 %) |
T2 | 9 (13.4 %) |
T3 | 53 (79.1 %) |
T4 | 4 (6 %) |
Lymph node metastases | |
N0 | 13 (19.4 %) |
N+ | 54 (80.6 %) |
Grade of differentiation (N = 60) | |
Low grade | 17 (28.3 %) |
Moderate-High grade | 43 (71.7 %) |
LVI (N = 63) | |
Yes | 6 (9.5 %) |
No | 57 (90.4 %) |
Tumor size, cm, median (IQR) | 5 (4; 6) |
Anal verge distance, cm, median (IQR) | 8 (5; 10) |
Neoadjuvant chemoradiotherapy | |
RDT- Flouropyrimidines | 54 (80.6 %) |
RDT- Flouropyrimidines - Oxaliplatin | 13 (19.4 %) |
T downstaging | |
Yes | 36 (53.7 %) |
No | 31 (46.3 %) |
Tumor Regression Grading | |
TRG 0 - 1 | 31 (46.3 %) |
TRG 2 - 3 | 36 (53.7 %) |
Responder | |
Yes | 45 (67.2 %) |
No | 22 (32.8 %) |