From: A cohort analysis of men with a family history of BRCA1/2 and Lynch mutations for prostate cancer
Clinico-pathological parameter | Patients diagnosed with prostate cancer (n = 3) | BRCA1 +ve case | BRCA2 +ve case | Lynch +ve case |
---|---|---|---|---|
Age | Mean 60 years old (range: 55–66) | 66 | 60 | 55 |
PSA (ng/ml) | 4.8 | 4.1 | 11.1 | |
Gleason score | 6 (3 + 3) | 3 + 3 | 3 + 3 | 3 + 3 |
TNM stage | T1c-T3N0M0/X | T1cN0Mx | T1cN0Mx | T3N0M0 |
Treatment/management | Active surveillance | Active surveillance | Radical prostatectomy |