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Table 1 Pre- and post- treatment characteristics and pathologic outcomes of men undergoing radical prostatectomy at University of Pennsylvania, 1990–2012

From: The impact of body mass index on treatment outcomes for patients with low-intermediate risk prostate cancer

 

Body mass index (kg/m2)

 

p-value

 

<25

%

25–30

%

>30

%

 

iPSA (ng/ml)

      

0.95b

 median

5.1

 

5.4

 

5.2

  

 mean

6.59

 

6.73

 

6.76

  

 IQR

3.9–6.8

 

4.2–7.2

 

4.1–7.2

  

Age (years)

      

0.37b

 median

60

 

60

 

59

  

 mean

59.1

 

59.2

 

58.6

  

 IQR

54–64

 

54–64

 

54–63

  

Biopsy Gleason Score

      

0.46a

  ≤ 6

150

82

459

76

293

77

 

 7

25

14

102

17

61

16

 

 8 to 10

7

4

40

7

73

6

 

Clinical T-stage

      

0.99a

 T1c

121

80

392

81

251

80

 

 T2a

24

16

73

15

51

16

 

 T2b

3

2

9

2

6

2

 

 T2c

3

2

12

2

5

2

 

Race

      

<0.001 a

 white

149

83

487

82

270

71

 

 African-American/Black

31

17

106

18

112

29

 

 other

4

2

9

2

2

0.5

 

Pathologic Gleason Score

      

0.001 a

  ≤ 6

106

58

321

53

165

43

 

 7

71

39

252

42

186

48

 

 8 to 10

7

4

29

5

33

9

 

Nodal Status

      

0.47a

 pN0

184

100

592

99

379

99

 

 pN1

0

0

3

1

3

1

 

Extraprostatic spread

39

21

130

22

117

30

0.004 a

Seminal Vesicle invasion

9

5

29

5

26

7

0.39a

Positive surgical margin

19

10

108

18

78

21

0.01 a

Additional Radiotherapy

1

0.6

11

2

8

2

0.39a

Hormonal Therapy

7

4

30

5

16

4

0.51a

No. of patients

184

 

602

 

384

  
  1. NOTE. Boldfaced values represent statistically significant differences between groups
  2. Abbreviations: iPSA initial prostate-specific antigen, IQR interquartile range
  3. a P value derived from Person’s chi-square test
  4. b P value derived from analysis of variance model