Table 3 Influence of potential prognostic factors on bone survival in multivariate analysis

Age

1.01

0.99–1.02

0.09

1.01

1.00–1.02

0.025

Gender

 Female

Reference

 Male

1.27

1.01–1.60

0.04

1.07

0.83–1.38

0.59

KPS

  > =80 %

Reference

  < 80 %

1.27

1.04–1.55

0.02

1.11

0.91–1.35

0.30

Primary site

 Breast cancer

Reference

 NSCLC

2.77

1.99–3.86

<0.0001

2.00

1.43–2.80

<0.0001

 Renal cancer

0.84

0.53–1.33

0.47

0.85

0.54–1.33

0.47

Localization of metastases

 Thoracic

Reference

 Lumbar

1.07

0.87–1.31

0.53

0.90

0.73–1.11

0.31

Number of metastases

 1

Reference

  > 1

1.16

0.95–1.41

0.13

1.35

1.11–1.65

0.003

Other distant metastases

 Liver yes

Reference

  no

0.72

0.56–0.92

0.008

0.71

0.54–0.92

0.003

 Brain yes

Reference

  no

0.84

0.63–1.11

0.22

0.85

0.63–1.16

0.32

 Lung yes

Reference

  no

1.27

0.99–1.62

0.06

1.05

0.79–1.40

0.73

 Skin yes

Reference

  no

1.09

0.69–1.72

0.71

0.91

0.44–1.85

0.79

Bisphosphonates

 yes

Reference

 no

1.19

0.91–1.56

0.21

1.07

0.79–1.44

0.66

Chemotherapy

 yes

Reference

 no

0.84

0.68–1.02

0.08

0.97

0.79–1.19

0.79

Orthopedic corset

 yes

Reference

 no

0.84

0.67–1.06

0.14

0.77

0.62–0.96

0.02

Radiotherapy schedule

  > 30 Gy

Reference

  < =30 Gy

1.27

0.99–1.63

0.06

1.08

0.86–1.35

0.53