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Table 10 Prognostic factors for overall survival in CRC stage IV

From: Significance of glycolytic metabolism-related protein expression in colorectal cancer, lymph node and hepatic metastasis

  Overall survival
Variable Univariate analysis Multivariate analysis
  HR 95 % CI p HR 95 % CI p
Age (<45 years) 2.116 0.938 – 4.774 0.071 0.898 0.271 - 2979 0.860
Localization (rectum) 0.684 0.350 – 1.447 0.267    
CEA (>5 ng/mL) 2.017 1.117 – 3.641 0.020 1.834 0.946 – 3.553 0.072
Differentiation (Poorly/undifferentiated) 2.748 1.470 – 5.138 0.002 3.488 1.563 – 7.782 0.002
Spread lymph node (present) 1.156 0.638 – 2.093 0.633    
Vessel invasion (present) 1.312 0.733 – 2.351 0.361    
MCT1 (+) 0.394 0.186 – 0.834 0.015 0.694 0.310 – 1.597 0.390
MCT4 (+) 1.429 0.767 – 2.664 0.261    
CD147 (+) 0.779 0.412 – 1.473 0.442    
GLUT1 (+) 1.169 0.642 – 2.129 0.610