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Table 10 Prognostic factors for overall survival in CRC stage IV

From: Significance of glycolytic metabolism-related protein expression in colorectal cancer, lymph node and hepatic metastasis

 

Overall survival

Variable

Univariate analysis

Multivariate analysis

 

HR

95 % CI

p

HR

95 % CI

p

Age (<45 years)

2.116

0.938 – 4.774

0.071

0.898

0.271 - 2979

0.860

Localization (rectum)

0.684

0.350 – 1.447

0.267

   

CEA (>5 ng/mL)

2.017

1.117 – 3.641

0.020

1.834

0.946 – 3.553

0.072

Differentiation (Poorly/undifferentiated)

2.748

1.470 – 5.138

0.002

3.488

1.563 – 7.782

0.002

Spread lymph node (present)

1.156

0.638 – 2.093

0.633

   

Vessel invasion (present)

1.312

0.733 – 2.351

0.361

   

MCT1 (+)

0.394

0.186 – 0.834

0.015

0.694

0.310 – 1.597

0.390

MCT4 (+)

1.429

0.767 – 2.664

0.261

   

CD147 (+)

0.779

0.412 – 1.473

0.442

   

GLUT1 (+)

1.169

0.642 – 2.129

0.610

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