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Fig. 5 | BMC Cancer

Fig. 5

From: Efficient generation of patient-matched malignant and normal primary cell cultures from clear cell renal cell carcinoma patients: clinically relevant models for research and personalized medicine

Fig. 5

Differentially expressed genes in VHLmut vs. VHLwt cells. a Heatmap showing the 593 differentially expressed protein-coding genes between VHLmut and VHLwt cells (cut-off of p ≤ 0.01 and 2-fold change). b Gene set enrichment analysis (GSEA) plots of the 211 VHLmut-associated genes (left) and 382 VHLwt-associated genes (right) in the TCGA ccRCC dataset. NES = normalized enrichment score; FDR q-val = false discovery rate q value. A gene set is considered significant with FDR < 0.25

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BMC Cancer

ISSN: 1471-2407

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