|
Study
|
Country (Ethnicity)
|
Form of disease
|
Cases/Control
|
HWE
|
Smoking status
|
Genotyping methods
|
|---|
|
Sample size
|
Genotype distribution
|
|---|
|
rs689466 (−1195G > A)
| |
GG
|
GA
|
AA
| | | |
|
Chiang 2008
|
China (Asian)
|
OSCC
|
368/441
|
80/114
|
187/235
|
101/92
|
Yes
|
Mixed
|
PCR-RFLP
|
|
Peters 2009
|
Netherlands (Caucasian)
|
HNSCC
|
431/438
|
275/260
|
134/163
|
22/15
|
Yes
|
Mixed
|
PCR
|
|
Mittal 2010
|
India (Asian)
|
OSCC
|
193/137
|
3/5
|
57/32
|
133/100
|
Yes
|
Smokers
|
PCR-RFLP
|
|
Chang 2013
|
China (Asian)
|
HNSCC
|
313/295
|
93/90
|
146/148
|
74/57
|
Yes
|
Mixed
|
Taqman
|
|
Niu 2014
|
China (Asian)
|
HNSCC
|
259/1035
|
61/222
|
126/542
|
72/271
|
Yes
|
Mixed
|
Taqman
|
|
OSCC
|
140/1035
|
44/222
|
80/542
|
25/271
|
Yes
|
Mixed
|
Taqman
|
|
LSCC
|
90/1035
|
17/222
|
46/542
|
27/271
|
Yes
|
Mixed
|
Taqman
|
|
rs5275 (8473 T > C)
| |
TT
|
TC
|
CC
| | | |
|
Campa 2007
|
European (multicenter)
|
HNSCC
|
553/711
|
252/313
|
237/321
|
44/77
|
Yes
|
Mixed
|
TaqMan
|
|
OSCC
|
252/711
|
113/313
|
117/321
|
22/77
|
Yes
|
Mixed
|
TaqMan
|
|
LSCC
|
281/711
|
139/313
|
120/321
|
22/77
|
Yes
|
Mixed
|
TaqMan
|
|
Mittal 2010
|
India (Asian)
|
OSCC
|
135/59
|
74/24
|
53/34
|
8/1
|
No
|
Smokers
|
PCR-RFLP
|
|
Chang 2013
|
China (Asian)
|
HNSCC
|
313/295
|
209/199
|
89/86
|
15/10
|
Yes
|
Mixed
|
Taqman
|
|
Niu 2014
|
China (Asian)
|
HNSCC
|
258/1032
|
177/691
|
72/316
|
9/25
|
Yes
|
Mixed
|
Taqman
|
|
OSCC
|
168/1032
|
118/691
|
45/316
|
5/25
|
Yes
|
Mixed
|
Taqman
|
|
LSCC
|
90/1032
|
59/691
|
27/316
|
4/25
|
Yes
|
Mixed
|
Taqman
|
|
rs20417 (−765G > C)
| |
GG
|
GC
|
CC
| | | |
|
Lin 2008
|
China (Asian)
|
OSCC
|
297/280
|
193/107
|
104/173
|
0/0
|
Yes
|
Mixed
|
PCR–RFLP
|
|
Chiang 2008
|
China (Asian)
|
OSCC
|
178/205
|
136/166
|
42/39
|
0/0
|
Yes
|
Mixed
|
PCR–RFLP
|
|
Peters 2009
|
Netherlands (Caucasian)
|
HNSCC
|
428/433
|
321/321
|
99/99
|
8/13
|
Yes
|
Mixed
|
PCR
|
|
Mittal 2010
|
India (Asian)
|
OSCC
|
176/96
|
92/41
|
78/49
|
6/6
|
Yes
|
Smokers
|
PCR–RFLP
|
|
Lakshmi 2012
|
India (Asian)
|
OSCC
|
150/150
|
110/142
|
28/6
|
12/2
|
No
|
Mixed
|
PCR–RFLP
|
- OSCC oral squamous cell carcinoma; HNSCC, head and neck squamous cell carcinoma; LSCC laryngeal squamous cell carcinoma; HWE Hardy–Weinberg Equilibrium
