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Fig. 7 | BMC Cancer

Fig. 7

From: Combination of VP3 and CD147-knockdown enhance apoptosis and tumor growth delay index in colorectal tumor allograft

Fig. 7

Apoptosis in treated mice CT26 colon cancer cell-induced tumor determined by TUNEL assay at day 25 post-treatment. a Tumor tissue with nick-labeling fragmented DNA. Apoptotic cells are stained dark brown while viable cells stained green color, 200×. Magnifying: shows brownish to darkish labeled nuclear granules. b Apoptotic index of tumor tissue. Error bars represent the standard error of the mean. Means with different letters are significantly (p < 0.05) different. CUT = Untreated control, CLacZ = pVIVO1-GFP/LacZ control, Czeo = psiRNA-h7SKzeo control, TVP3 = Treated with pVIVO1-GFP/VP3 (VP3), TshCD = Treated with psiRNA-CD147/2 (shCD147/2), TV-shCD(50) and TV-shCD(100) = Treated with 50 and 100 μg dose of VP3-shCD147/2 combination respectively

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