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Table 3 Relationships between pleural fluid OPN, VEGF, uPA, and PAI-1 concentrations in patients with malignant pleural effusion

From: Pleural fluid osteopontin, vascular endothelial growth factor, and urokinase-type plasminogen activator levels as predictors of pleurodesis outcome and prognosticators in patients with malignant pleural effusion: a prospective cohort study

  All Male Female Female Lung cancer Breast cancer Distant metastasis
Pre-menopausal Post-menopausal Yes No
OPN & VEGF
r 0.466 0.750 0.279 −0.105 0.824 0.493 0.709 0.503 0.655
p value <0.001 0.032 0.005 0.088 0.023 0.010 0.029 0.001 0.462
VEGF & uPA
r 0.244 0.894 0.282 0.717 −0.047 0.360 −0.034 0.344 −0.108
p value < 0.001 0.006 < 0.001 0.010 0.002 < 0.001 0.005 < 0.001 0.010
OPN & uPA
r 0.068 0.642 0.054 0.074 −0.009 0.081 0.008 0.145 −0.104
p value < 0.001 0.017 < 0.001 0.011 < 0.001 < 0.001 0.001 < 0.001 0.010
uPA & PAI-1
r −0.682 −0.612 −0.689 −0.808 −0.618 −0.679 −0.717 −0.652 −0.831
p value < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001 < 0.001
  1. r, correlation coefficient