Association of preoperative EpCAM Circulating Tumor Cells and peripheral Treg cell levels with early recurrence of hepatocellular carcinoma following radical hepatic resection

Table 3 Association of Treg/CD4⁺ with clinical characteristics

Clinical characteristics		Treg/CD4⁺ <5.07 %	Treg/CD4 ≥ 5.07 %	P
Age (y)	≤50	16	7	0.040*
Age (y)	>50	24	2	0.040*
Sex	Male	13	0	0.046*
Sex	Female	27	9	0.046*
HBsAg	Negative	8	1	0.534
HBsAg	Postive	32	8	0.534
HBeAg	Negative	30	6	0.609
HBeAg	Postive	10	3	0.609
HBVDNA	<5*10²	25	6	0.815
HBVDNA	>5*10²	15	3	0.815
Child-Pugh score	A	39	9	0.632
Child-Pugh score	B	1	0	0.632
Liver cirrhosis	No	10	2	0.861
Liver cirrhosis	Yes	30	7	0.861
ALT (U/L)	≤75	26	7	0.460
ALT (U/L)	>75	14	2	0.460
AFP (ng/ml)	≤400	32	7	0.881
AFP (ng/ml)	>400	8	2	0.881
Tumor number	Single	36	8	0.921
Tumor number	Multiple	4	1	0.921
Tumor size (cm)	≤5	25	4	0.319
Tumor size (cm)	>5	15	5	0.319
Tumor encapsulation	Complete	17	4	0.915
Tumor encapsulation	None	23	5	0.915
Satellite lesion	No	38	6	0.011*
Satellite lesion	Yes	2	3	0.011*
Vascular invasion	No	22	3	0.240
Vascular invasion	Yes	18	6	0.240
Edmondson stage	I-II	25	6	0.815
Edmondson stage	II-IV	15	3	0.815
BCLC stage	0 + A	37	7	0.187
BCLC stage	B + C	3	2	0.187

ISSN: 1471-2407