Table 1 Immunohistochemistry demonstrates only weak IGF1R expression in uncultured cartilage tumours
From: No preclinical rationale for IGF1R directed therapy in chondrosarcoma of bone
Diagnose | Weak IGF1R positivity | |
|---|---|---|
Enchondroma | 3/5 (60Â %) | |
Osteochondroma | 2/7 (29Â %) | |
Central Conventional chondrosarcoma | 32/71 (45Â %) | |
| Â | Grade I | 8/28 (29Â %) |
| Â | Grade II | 15/29 (51Â %) |
| Â | Grade III | 9/14 (64Â %) |
Peripheral Conventional chondrosarcoma | 14/34 (41Â %) | |
| Â | Grade I | 8/21 (38Â %) |
| Â | Grade II | 5/10 (50Â %) |
| Â | Grade III | 1/3 (33Â %) |
Dedifferentiated chondrosarcoma | 11/32 (34Â %) | |
Mesenchymal chondrosarcoma | 0/18 (0Â %) | |
Clear cell chondrosarcoma | 1/20 (5Â %) | |
Total | 63/187 (34Â %) | |