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Fig. 2 | BMC Cancer

Fig. 2

From: New anti-cancer chemicals Ertredin and its derivatives, regulate oxidative phosphorylation and glycolysis and suppress sphere formation in vitro and tumor growth in EGFRvIII-transformed cells

Fig. 2

High throughput screening system developed to identify inhibitors of anchorage-independent growth induced by EGFRvIII. a Outline of the screening system. b Potency of protein kinase inhibitors in the screening systems. NIH3T3/EGFRvIII cells were seeded on ULAS 96-well plates for 3D-culture (red line). NIH3T3 cells were seeded on normal tissue culture plates for 2D-culture (blue line). Each inhibitor was added to the medium on day 0. Three days after inoculation, viable cells were counted and the extent of inhibition was calculated

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BMC Cancer

ISSN: 1471-2407

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