Skip to main content

Advertisement

Table 3 Women with CIN2 or higher: Screening test results for cross-reacting samples

From: Cross-reactivity profiles of hybrid capture II, cobas, and APTIMA human papillomavirus assays: split-sample study

     HPV test result   
Case number Grade of CIN Cytology Detected genotypes by CLART HC2, relative light units per cut-off cobas, cycle threshold APTIMA, signal per cut-off
Cross-reactivity to low-risk genotypes
1 Grade 2 Atypical 70, 71, 81, 84 Positive (cross-reacting), 9.55 Negative Positive (cross-reacting), 3.44
2 Grade 2 Normal 53, 66, 83 Positive (cross-reacting), 3.58 Positive, other high-risk genotypes: 30.1 Negative
3 Grade 3 Low-grade 82 Positive (cross-reacting), 2.70 Positive (cross-reacting), genotype 16: 37.3 Negative
4 Grade 3 High-grade 42, 61 Positive (cross-reacting), 5.74 Negative Negative
5 Grade 3 High-grade 82 Positive (cross-reacting), 11.06 Negative Negative
6 Cervical cancer High-grade 70 Positive (“cross-reacting”), 21.43 Positive (“cross-reacting”), genotype 18: 39.5 Positive (“cross-reacting”), 0.84
Cross-reactivity to unconfirmed genotypes
7 Grade 3 Atypical None Positive (CLART negative), 2.14 Positive (CLART negative), other high-risk genotypes: 34.0 Positive (CLART negative), 14.92