Table 3 Women with CIN2 or higher: Screening test results for cross-reacting samples
HPV test result | ||||||
|---|---|---|---|---|---|---|
Case number | Grade of CIN | Cytology | Detected genotypes by CLART | HC2, relative light units per cut-off | cobas, cycle threshold | APTIMA, signal per cut-off |
Cross-reactivity to low-risk genotypes | ||||||
1 | Grade 2 | Atypical | 70, 71, 81, 84 | Positive (cross-reacting), 9.55 | Negative | Positive (cross-reacting), 3.44 |
2 | Grade 2 | Normal | 53, 66, 83 | Positive (cross-reacting), 3.58 | Positive, other high-risk genotypes: 30.1 | Negative |
3 | Grade 3 | Low-grade | 82 | Positive (cross-reacting), 2.70 | Positive (cross-reacting), genotype 16: 37.3 | Negative |
4 | Grade 3 | High-grade | 42, 61 | Positive (cross-reacting), 5.74 | Negative | Negative |
5 | Grade 3 | High-grade | 82 | Positive (cross-reacting), 11.06 | Negative | Negative |
6 | Cervical cancer | High-grade | 70 | Positive (“cross-reacting”), 21.43 | Positive (“cross-reacting”), genotype 18: 39.5 | Positive (“cross-reacting”), 0.84 |
Cross-reactivity to unconfirmed genotypes | ||||||
7 | Grade 3 | Atypical | None | Positive (CLART negative), 2.14 | Positive (CLART negative), other high-risk genotypes: 34.0 | Positive (CLART negative), 14.92 |