Table 1 Clinical features and survival of study participants (N = 115)
Clinical features | N (%) | Survival | ||
|---|---|---|---|---|
1 yr.(%) | 2 yrs. (%) | p | ||
Gender | ||||
 Male | 88 (76.52) | 63.67 | 38.98 | |
 Female | 27 (23.48) | 62.96 | 57.89 | 0.523 |
Age (y.o) | ||||
 <60 | 37 (32.17) | 56.76 | 29.63 | |
 ≧60 | 78 (74.26) | 66.67 | 45.28 | 0.207 |
ECOG | ||||
 0 | 49 (42.61) | 75.51 | 54.29 | |
 1 | 53 (46.09) | 58.49 | 36.36 | |
 2 | 13 (11.3) | 46.15 | 20 | 0.118 |
Child-Pugh score | ||||
 A | 104 (90.43) | 68.27 | 47.14 | |
 B | 11 (9.57) | 27.27 | 12.5 | <0.001 |
AJCC stage (7th) | ||||
 I | 21 (18.26) | 85.71 | 78.57 | |
 II | 18 (15.65) | 72.22 | 60 | |
 IIIA | 26 (22.61) | 69.23 | 40 | |
 IIIB | 27 (23.48) | 37.03 | 11.11 | |
 IIIC | 3 (2.61) | 100 | 0 | |
 IV | 20 (17.39) | 55 | 37.5 | 0.001 |
BCLC | ||||
 A | 12 (10.44) | 83.33 | 75 | |
 B | 23 (20) | 86.26 | 56.25 | |
 C | 80 (69.56) | 55 | 31.48 | 0.080 |
Tumor type | ||||
 Solitary | 38 (33.04) | 81.58 | 62.5 | |
 Multiple | 69 (60) | 56.52 | 31.25 | |
 Diffuse | 8 (6.96) | 37.5 | 33.33 | <0.001 |
Tumor site | ||||
 Right | 91 (79.13) | 64.83 | 42.86 | |
 Left | 14 (13.04) | 53.33 | 38.46 | |
 Bilateral | 10 (8.7) | 60 | 0 | 0.506 |
Max. tumor diameter (cm) | ||||
 ≦4 | 40 (34.78) | 75 | 55.17 | |
 > 4-9 | 47 (40.87) | 68.82 | 36.67 | |
 ≧10 | 28 (23.48) | 48.15 | 26.32 | 0.187 |
Portal vein tumor thrombosis | ||||
 Yes | 34 (29.56) | 35.29 | 12 | |
 No | 81 (70.43) | 75.31 | 53.7 | <0.001 |
Hepatitis virus | ||||
 B | 59 (51.3) | 66.1 | 36.58 | |
 C | 42 (36.52) | 59.52 | 46.43 | |
 Non B non C | 11 (9.57) | 81.82 | 77.78 | |
 B + C | 3 (2.61) | 66.67 | 0 | 0.576 |
AFP Level (ng/ml) | ||||
 ≦20 | 41 (34.78) | 82.93 | 62.5 | |
 > 20-400 | 31 (27.84) | 51.61 | 17.65 | |
 ≧400 | 43 (37.39) | 53.49 | 34.48 | 0.013 |
Biochemical changes | ||||
Albumin (g/dl) [N = 109] | ||||
 <3.5 | 26 (23.85) | 46.15 | 31.81 | |
 ≥3.5 | 83 (76.15) | 67.47 | 44.64 | 0.027 |
Alkaline Phosphatase (IU/L) [N = 104] | ||||
 ≧129 | 37 (35.58) | 59.45 | 42.57 | |
 <129 | 67 (64.42) | 64.18 | 36.95 | 0.893 |
Platelet (10^3/uL) [N = 109] | ||||
 <150 | 52 (47.71) | 63.46 | 35 | |
 ≧150 | 57 (52.29) | 68.42 | 48.65 | 0.291 |
BED | ||||
 ≦72 Gy10 | 65 (56.52) | 56.92 | 28.2 | |
 73-88 Gy10 | 8 (6.96) | 62.5 | 28.57 | |
 ≧89 Gy10 | 42 (36.52) | 76.19 | 56.25 | 0.038 |
Previous treatment | ||||
 Yes | 52 (45.22) | 50 | 37.14 | |
 No | 63 9(54.78) | 55.56 | 43.18 | 0.584 |