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Table 3 Multivariate analysis of risk factors affecting patient survival

From: Serum fibrinogen levels are positively correlated with advanced tumor stage and poor survival in patients with gastric cancer undergoing gastrectomy: a large cohort retrospective study

Variable HR (95 % CI) p
Lymph node dissection (radical vs. non-radical) 2.66 (2.20–3.22) < 0.0001
Lymph node dissection (radical vs. palliative) 16.97 (9.07–31.72) < 0.0001
Multi-organ involvement (yes vs. no) 2.06 (1.50–2.84) < 0.0001
T stage (2 vs. 1) 0.72 (0.44–1.16) 0.1744
T stage (3 vs. 1) 1.14 (0.74–1.78) 0.5501
T stage (4 vs. 1) 1.33 (0.86–2.04) 0.1965
N stage (1 vs. 0) 1.37 (0.96–1.97) 0.0851
N stage (2 vs. 0) 2.44 (1.61–3.70) < 0.0001
N stage (3 vs. 0) 3.22 (2.09–4.94) < 0.0001
Metastasis (yes vs. no) 81.97 (10.49–640.70) < 0.0001
TNM stage (2 vs. 1) 3.00 (1.71–5.26) 0.0001
TNM stage (3 vs. 1) 3.37 (1.68–6.76) 0.0006
TNM stage (4 vs. 1) 0.08 (0.01–0.60) 0.0148
Differentiation (medium and good vs. poor) 0.65 (0.51–0.83) 0.0006
Differentiation (mucous vs. poor) 0.53 (0.34–0.83) 0.0054
Differentiation (papillary vs. poor) 0.94 (0.35–2.55) 0.9075
Differentiation (mixed and others vs. poor) 0.90 (0.75–1.09) 0.2895
Differentiation (Signet Ring vs. poor) 0.90 (0.54–1.49) 0.6717
Fibrinogen (g/L) (>4 vs. ≤4) 1.36 (1.14–1.62) 0.0008
Carbohydrate antigen 19-9 (≥37 vs. < 37) 1.39 (1.08–1.79) 0.0115