Table 3 Multivariate analysis of risk factors affecting patient survival

Lymph node dissection (radical vs. non-radical)

2.66 (2.20–3.22)

< 0.0001

Lymph node dissection (radical vs. palliative)

16.97 (9.07–31.72)

< 0.0001

Multi-organ involvement (yes vs. no)

2.06 (1.50–2.84)

< 0.0001

T stage (2 vs. 1)

0.72 (0.44–1.16)

0.1744

T stage (3 vs. 1)

1.14 (0.74–1.78)

0.5501

T stage (4 vs. 1)

1.33 (0.86–2.04)

0.1965

N stage (1 vs. 0)

1.37 (0.96–1.97)

0.0851

N stage (2 vs. 0)

2.44 (1.61–3.70)

< 0.0001

N stage (3 vs. 0)

3.22 (2.09–4.94)

< 0.0001

Metastasis (yes vs. no)

81.97 (10.49–640.70)

< 0.0001

TNM stage (2 vs. 1)

3.00 (1.71–5.26)

0.0001

TNM stage (3 vs. 1)

3.37 (1.68–6.76)

0.0006

TNM stage (4 vs. 1)

0.08 (0.01–0.60)

0.0148

Differentiation (medium and good vs. poor)

0.65 (0.51–0.83)

0.0006

Differentiation (mucous vs. poor)

0.53 (0.34–0.83)

0.0054

Differentiation (papillary vs. poor)

0.94 (0.35–2.55)

0.9075

Differentiation (mixed and others vs. poor)

0.90 (0.75–1.09)

0.2895

Differentiation (Signet Ring vs. poor)

0.90 (0.54–1.49)

0.6717

Fibrinogen (g/L) (>4 vs. ≤4)

1.36 (1.14–1.62)

0.0008

Carbohydrate antigen 19-9 (≥37 vs. < 37)

1.39 (1.08–1.79)

0.0115