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Table 1 CDX2 expression in relation to clinicopathological characteristics in CRC

From: SOX2 expression is associated with a cancer stem cell state and down-regulation of CDX2 in colorectal cancer

  CDX2 expression  
  <5 % 5–50 % >50 % P valuea
Frequencies, n (%) 62 (14.4) 125 (29.0) 244 (56.6)  
Sex, n (%)     0.667
 Male 33 (14.3) 63 (27.3) 135 (58.4)  
 Female 29 (14.5) 62 (31.0) 109 (54.5)  
Age, n (%)     0.275
 ≤59 years 16 (21.1) 18 (23.7) 42 (55.3)  
 60–69 years 16 (14.7) 29 (26.6) 64 (58.7)  
 70–79 years 20 (12.9) 54 (34.8) 81 (52.3)  
 ≥80 years 10 (11.0) 24 (26.4) 57 (62.6)  
TNM stage, n (%)b     <0.001
 I 2 (3.0) 21 (31.8) 43 (65.2)  
 II 19 (11.2) 36 (21.3) 114 (67.5)  
 III 17 (19.3) 32 (36.4) 39 (44.3)  
 IV 24 (24.2) 33 (33.3) 42 (42.4)  
Localization, n (%)b     <0.001
 Right colon 41 (29.5) 27 (19.4) 71 (51.1)  
 Left colon 9 (7.1) 39 (30.7) 79 (62.2)  
 Rectum 12 (7.5) 59 (36.6) 90 (55.9)  
Grade, n (%)b     <0.001
 Highly to moderately differentiated 13 (6.3) 45 (22.0) 147 (71.7)  
 Moderately to poorly differentiated 49 (22.5) 80 (36.7) 89 (40.8)  
  1. aχ2 test
  2. bThe following numbers of missing cases were present: TNM stage, 9; localization, 4; grade, 8