Fig. 3From: Utilizing native fluorescence imaging, modeling and simulation to examine pharmacokinetics and therapeutic regimen of a novel anticancer prodrugCorrelation between MCHB fluorescence and cell killing in vitro. a MCHB fluorescence [relative units (RFU)] is shown in relation to loss of cell viability with time after CNOB (15 μM) addition to 4T1 cells constitutively generating HChrR6. Nonlinear regression was used for curve fitting. Error bars represent standard deviation (SD; n = 4). b Using GraphPad Prism software, correlation between viability and fluorescence (RFU) at each time point was calculated and is presented as Pearson’s r value and probability of correlation (p value)Back to article page