Fig. 7
From: Etoposide damages female germ cells in the developing ovary
Etoposide primarily targets oocytes prior to follicle formation and granulosa cells after follicle formation. Follicles were categorised as unhealthy due to: unhealthy oocyte (OOC) only (i); unhealthy granulosa cells (GCs) only (ii); or unhealthy oocyte and granulosa cells (OOC + GCs) (iii), in fetal (a) or neonatal (b) mouse ovaries exposed to etoposide. Bars denote mean ± SEM; n = 6 for all groups. Stars denote significant differences relative to control (*p < 0.05)