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Table 2 Univariate analyses of survival in vulvar cancer patients

From: The overexpression of p16 is not a surrogate marker for high-risk human papilloma virus genotypes and predicts clinical outcomes for vulvar cancer

Variables

Categories

Overall survival

p

HR

95 % CI

Nodal status

Negative for metastases

1

1.59–5.22

0.0005

Positive for metastases

2.88

Adjuvant RTX

Yes

1

2.22–7.30

0.000005

No

4.02

Histologic grade

Low (G1)

1

1.65–7.15

0.001

High (G2 + G3)

3.43

p16 status

Positive

1

1.11–3.81

0.0216

Negative

2.06

FIGO stage

I, II, III, IV

1.62

1.23–2.12

0.000592

Depth of invasion

Continuous

1.05

0.96–1.15

0.283261

Age

<60

1

1.12–5.59

0.025436

>60

2.5