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Table 6 Cox multivariate analysis of relative risk of death from pancreatic ductal adenocarcinoma by β-catenin and PROX1 expression

From: PROX1 and β-catenin are prognostic markers in pancreatic ductal adenocarcinoma

β-catenin PROX1 Combined
β-catenin expression HR (95 % CI) P-value PROX1 expression HR (95 % CI) P-value β-catenin and PROX expression (HR 95 % CI) P-value
Low 1.00   Low 1.00   Low 1.00  
High 0.54 (0.35–0.82) 0.004 High 0.63 (0.42–0.95) 0.026 Moderate 0.61 (0.36–1.03) 0.063
       High 0.46 (0.28–0.76) 0.002
  1. Abbreviations CI Confidence interval, HR Hazard ratio. Multivariate analysis included adjustment for age, gender, stage (IA-IIA, IIB and III) and lymph node ratio (≥/< 20 %), postoperative adjuvant therapy, and perivascular invasion