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Table 6 Cox multivariate analysis of relative risk of death from pancreatic ductal adenocarcinoma by β-catenin and PROX1 expression

From: PROX1 and β-catenin are prognostic markers in pancreatic ductal adenocarcinoma

β-catenin

PROX1

Combined

β-catenin expression

HR (95 % CI)

P-value

PROX1 expression

HR (95 % CI)

P-value

β-catenin and PROX expression

(HR 95 % CI)

P-value

Low

1.00

 

Low

1.00

 

Low

1.00

 

High

0.54 (0.35–0.82)

0.004

High

0.63 (0.42–0.95)

0.026

Moderate

0.61 (0.36–1.03)

0.063

      

High

0.46 (0.28–0.76)

0.002

  1. Abbreviations CI Confidence interval, HR Hazard ratio. Multivariate analysis included adjustment for age, gender, stage (IA-IIA, IIB and III) and lymph node ratio (≥/< 20 %), postoperative adjuvant therapy, and perivascular invasion