Table 2 Association of clinicopathological parameters and β-catenin expression
From: PROX1 and β-catenin are prognostic markers in pancreatic ductal adenocarcinoma
β-catenin expression | |||
|---|---|---|---|
Low (0–1) | High (2–3) | ||
n(%) | 53 (34.6) | 100 (65.4) | p-value |
Age, years | |||
< 65 | 28 (52.8) | 48 (48.0) | 0.613 |
≥ 65 | 25 (47.2) | 52 (52.0) | |
Gender | |||
Male | 32 (60.4) | 52 (52.0) | 0.394 |
Female | 21 (39.6) | 48 (48.0) | |
T | |||
1 | 3 (5.7) | 8 (8.0) | 0.602 |
2 | 14 (26.4) | 26 (26.0) | |
3 | 34 (64.2) | 65 (65.0) | |
4 | 2 (3.8) | 1 (1.0) | |
N | |||
0 | 15 (28.3) | 32 (32.0) | 0.714 |
1 | 38 (71.7) | 68 (68.0) | |
Stage (WHO) | |||
IA | 3 (5.7) | 6 (6.0) | 0.590 |
IB | 6 (11.3) | 12 (12.0) | |
IIA | 5 (9.4) | 14 (14.0) | |
IIB | 37 (69.8) | 67 (67.0) | |
III | 2 (3.8) | 1 (1.0) | |
Lymph node ratio | |||
< 20 % | 40 (75.5) | 77 (78.6) | 0.687 |
≥ 20 % | 13 (24.5) | 21 (21.4) | |
Missing | 2 | ||
Grade | |||
1 | 5 (10.9) | 17 (19.8) | 0.025 |
2 | 29 (63.0) | 60 (69.8) | |
3 | 12 (26.1) | 9 (10.5) | |
Missing | 7 | 14 | |
Perineural invasion | |||
Yes | 34 (77.3) | 66 (77.6) | 1.000 |
No | 10 (22.7) | 19 (22.4) | |
Missing | 9 | 15 | |
Perivascular invasion | |||
Yes | 19 (43.2) | 24 (30.0) | 0.169 |
No | 25 (56.8) | 56 (70.0) | |
Missing | 9 | 20 | |