Table 1 Association of clinicopathological parameters and PROX1 expression
From: PROX1 and β-catenin are prognostic markers in pancreatic ductal adenocarcinoma
PROX1 expression | |||
|---|---|---|---|
Low (0–1) | High (2–3) | ||
n(%) | 80 (51.9) | 74 (48.1) | p-value |
Age, years | |||
< 65 | 46 (57.5) | 30 (40.5) | 0.038 |
≥ 65 | 34 (42.5) | 44 (59.5) | |
Gender | |||
Male | 45 (56.3) | 40 (54.1) | 0.871 |
Female | 35 (43.7) | 34 (45.9) | |
T | |||
1 | 5 (6.3) | 7 (9.5) | 0.274 |
2 | 18 (22.5) | 22 (29.7) | |
3 | 56 (70.0) | 43 (58.1) | |
4 | 1 (1.3) | 2 (2.7) | |
N | |||
0 | 23 (28.8) | 25 (33.8) | 0.602 |
1 | 57 (71.2) | 49 (66.2) | |
Stage (WHO) | |||
IA | 4 (5.0) | 5 (6.8) | 0.550 |
IB | 8 (10.0) | 10 (13.5) | |
IIA | 11 (13.8) | 9 (12.2) | |
IIB | 56 (70.0) | 48 (64.9) | |
III | 1 (1.3) | 2 (2.7) | |
Lymph node ratio | |||
< 20 % | 57 (71.3) | 60 (83.3) | 0.086 |
≥ 20 % | 23 (28.7) | 12 (16.7) | |
Missing | 2 | ||
Grade | |||
1 | 10 (14.7) | 12 (19.0) | 0.543 |
2 | 47 (69.1) | 42 (66.7) | |
3 | 11 (16.2) | 9 (14.3) | |
Missing | 12 | 11 | |
Perineural invasion | |||
Yes | 49 (73.1) | 51 (82.3) | 0.291 |
No | 18 (26.9) | 11 (17.7) | |
Missing | 13 | 12 | |
Perivascular invasion | |||
Yes | 24 (36.9) | 19 (32.2) | 0.706 |
No | 41 (63.1) | 40 (67.8) | |
Missing | 15 | 15 | |