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Table 1 Association of clinicopathological parameters and PROX1 expression

From: PROX1 and β-catenin are prognostic markers in pancreatic ductal adenocarcinoma

PROX1 expression
  Low (0–1) High (2–3)  
n(%) 80 (51.9) 74 (48.1) p-value
Age, years    
  < 65 46 (57.5) 30 (40.5) 0.038
  ≥ 65 34 (42.5) 44 (59.5)  
Gender    
 Male 45 (56.3) 40 (54.1) 0.871
 Female 35 (43.7) 34 (45.9)  
T    
 1 5 (6.3) 7 (9.5) 0.274
 2 18 (22.5) 22 (29.7)  
 3 56 (70.0) 43 (58.1)  
 4 1 (1.3) 2 (2.7)  
N    
 0 23 (28.8) 25 (33.8) 0.602
 1 57 (71.2) 49 (66.2)  
Stage (WHO)    
 IA 4 (5.0) 5 (6.8) 0.550
 IB 8 (10.0) 10 (13.5)  
 IIA 11 (13.8) 9 (12.2)  
 IIB 56 (70.0) 48 (64.9)  
 III 1 (1.3) 2 (2.7)  
Lymph node ratio    
  < 20 % 57 (71.3) 60 (83.3) 0.086
  ≥ 20 % 23 (28.7) 12 (16.7)  
 Missing   2  
Grade    
 1 10 (14.7) 12 (19.0) 0.543
 2 47 (69.1) 42 (66.7)  
 3 11 (16.2) 9 (14.3)  
 Missing 12 11  
Perineural invasion    
 Yes 49 (73.1) 51 (82.3) 0.291
 No 18 (26.9) 11 (17.7)  
 Missing 13 12  
Perivascular invasion
 Yes 24 (36.9) 19 (32.2) 0.706
 No 41 (63.1) 40 (67.8)  
 Missing 15 15  
  1. Fischer exact-test was used for 2×2 tables and linear-by-linear association test for tables with more than two rows. Missing data excluded from the analyses