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Fig. 7 | BMC Cancer

Fig. 7

From: Combination of a third generation bisphosphonate and replication-competent adenoviruses augments the cytotoxicity on mesothelioma

Fig. 7

Influence of ZOL on viral progeny production. MSTO-211H and NCI-H28 cells were treated with Ad-delE1B55 (MSTO-211H: 4.5 × 103 vp/cell, NCI-H28: 2 × 103 vp/cell) or in combination of ZOL (MSTO-211H: 10 μM, NCI-H28: 80 μM) and the cell lysate was extracted at the indicated times. a The viral titers were assayed with the TCID50 method. Averages and SE bars are shown (n = 3). b Expression of E1A and hexon in cell lysate was probed with respective Ab. An upper band detected with anti-hexon Ab was due to a non-specific reaction and the lower band corresponded to hexon. α-Tubulin is used as a loading control

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BMC Cancer

ISSN: 1471-2407

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