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Table 4 FISH spots detected per CTC in a patient with an ALK-rearranged tumor depending on the step

From: Method for semi-automated microscopy of filtration-enriched circulating tumor cells

CTC ID

Number of FA-FISH spots

 

0.5 μm

0.6 μm

0.7 μm

0.8 μm

1

16

16

16

16

2

16

16

16

16

3

32

32

32

28

4

32

32

28

27

5

16

16

14

13

6

32

32

32

32

7

14

14

14

14

8

13

16

12

16

9

29

28

32

32

10

16

16

16

16

11

16

16

16

16

12

28

26

31

30

13

32

32

32

30

14

32

32

32

32

15

14

14

14

14

16

27

28

18

27

17

16

16

16

16

18

14

14

14

12

19

30

32

30

27

20

16

16

16

14

21

16

16

16

16

22

32

32

31

22

23

32

32

32

27

24

32

32

32

32

%a

79 %

92 %

75 %

58 %

  1. Abbreviations: ALK anaplastic lymphoma kinase gene; CTC, circulating tumor cell; FISH, fluorescence in situ hybridization
  2. aPercentage of cases where a higher number of FISH spots were observed
  3. The numbers in bold correspond to the highest number of spots for this CTC
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BMC Cancer

ISSN: 1471-2407

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