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Table 3 Univariable and multivariable analysis for predicting advanced pathological stage and high pathological grade PCa

From: Metabolic syndrome is associated with advanced prostate cancer in patients treated with radical retropubic prostatectomy: results from a multicentre prospective study

  Advanced pathological stage (≥ pT3a or N1) High pathological Gleason Score (≥4 + 3)
Crude OR p Multivariable p Crude OR p Multivariable p
Age, years OR: 1.051 (CI: 1.010-1.094) 0.014 OR: 1.044 (CI: 0.997-1.094) 0.006 OR: 1.021 (CI: 0.984-1.060) 0.268 OR: 1.001 (CI: 0.961-1.044) 0.949
TRUS Volume, ml OR: 0.994 (CI: 0.987-1.002) 0.155 OR: 0.993 (CI: 0.983-1.003) 0.173 OR: 0.997 (CI: 0.989-1.004) 0.356 OR: 0.998 (CI: 0.989-1.006) 0.594
PSA, ng/ml OR: 1.068 (CI: 1.033-1.134) 0.001 OR: 1.121 (CI: 1.060-1.185) 0.001 OR: 1.038 (CI: 1.012-1.065) 0.004 OR: 1.064 (CI: 1.024-1.106) 0.002
BMI, kg/m2 OR: 1.016 (CI: 0.945-1.092) 0.673    OR: 1.027 (CI: 0.957-1.102) 0.459   
MetS OR: 2.439 (CI: 1.492-3.987) 0.004 OR: 2.697 (CI: 1.481-4.913) 0.001 OR: 1.886 (CI: 1.164-3.054) 0.010 OR: 1.880 (CI: 1.066-3.316) 0.029
Waist, cm OR: 1.016 (CI: 0.990-1.043) 0.218    OR: 1.009 (CI: 0.984-1.034) 0.494   
Glycaemia, mg/dl OR: 1.007 (CI: 0.996-1.018) 0.203    OR: 1.007 (CI: 0.997-1.018) 0.181   
Trygliceridemia, mg/dl OR: 1.001 (CI: 0.997-1.005) 0.565    OR: 1.002 (CI: 0.998-1.005) 0.423   
HDL, mg/dl OR: 1.001 (CI: 0.983-1.019) 0.947    OR: 0.992 (CI: 0.974-1.010) 0.374   
Hypertension OR: 1.621 (CI: 0.987-2.662) 0.056    OR: 2.180 (CI: 1.330-3.575) 0.002   
  1. OR = Odds Ratio