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Table 3 Univariable and multivariable analysis for predicting advanced pathological stage and high pathological grade PCa

From: Metabolic syndrome is associated with advanced prostate cancer in patients treated with radical retropubic prostatectomy: results from a multicentre prospective study

 

Advanced pathological stage (≥ pT3a or N1)

High pathological Gleason Score (≥4 + 3)

Crude OR

p

Multivariable

p

Crude OR

p

Multivariable

p

Age, years

OR: 1.051 (CI: 1.010-1.094)

0.014

OR: 1.044 (CI: 0.997-1.094)

0.006

OR: 1.021 (CI: 0.984-1.060)

0.268

OR: 1.001 (CI: 0.961-1.044)

0.949

TRUS Volume, ml

OR: 0.994 (CI: 0.987-1.002)

0.155

OR: 0.993 (CI: 0.983-1.003)

0.173

OR: 0.997 (CI: 0.989-1.004)

0.356

OR: 0.998 (CI: 0.989-1.006)

0.594

PSA, ng/ml

OR: 1.068 (CI: 1.033-1.134)

0.001

OR: 1.121 (CI: 1.060-1.185)

0.001

OR: 1.038 (CI: 1.012-1.065)

0.004

OR: 1.064 (CI: 1.024-1.106)

0.002

BMI, kg/m2

OR: 1.016 (CI: 0.945-1.092)

0.673

  

OR: 1.027 (CI: 0.957-1.102)

0.459

  

MetS

OR: 2.439 (CI: 1.492-3.987)

0.004

OR: 2.697 (CI: 1.481-4.913)

0.001

OR: 1.886 (CI: 1.164-3.054)

0.010

OR: 1.880 (CI: 1.066-3.316)

0.029

Waist, cm

OR: 1.016 (CI: 0.990-1.043)

0.218

  

OR: 1.009 (CI: 0.984-1.034)

0.494

  

Glycaemia, mg/dl

OR: 1.007 (CI: 0.996-1.018)

0.203

  

OR: 1.007 (CI: 0.997-1.018)

0.181

  

Trygliceridemia, mg/dl

OR: 1.001 (CI: 0.997-1.005)

0.565

  

OR: 1.002 (CI: 0.998-1.005)

0.423

  

HDL, mg/dl

OR: 1.001 (CI: 0.983-1.019)

0.947

  

OR: 0.992 (CI: 0.974-1.010)

0.374

  

Hypertension

OR: 1.621 (CI: 0.987-2.662)

0.056

  

OR: 2.180 (CI: 1.330-3.575)

0.002

  
  1. OR = Odds Ratio