Univariate | Multivariate | ||||||
---|---|---|---|---|---|---|---|
Hazard ratio | (95 % CI) | P-value | Hazard ratio | (95 % CI) | P-value | ||
Progression-free survival | |||||||
EILD | Yes | 1.80 | 0.013 | 1.44 | 0.16 | ||
No | 1.11–2.88 | 0.86–2.41 | |||||
Age | ≦56≦56 | 0.76 | 0.14 | 0.76 | 0.19 | ||
>56 | 0.52–1.10 | 0.51–1.15 | |||||
PS | 0 | 1.41 | 0.089 | 1.49 | 0.073 | ||
1,2 | 0.95–2.10 | 0.96–2.31 | |||||
Comorbid disease | Yes | 1.44 | 0.12 | 1.51 | 0.13 | ||
No | 0.91–2.28 | 0.88–2.58 | |||||
DFI | ≦2.8≦2.8 | 1.41 | 0.069 | 1.27 | 0.27 | ||
>2.8 | 0.97–2.06 | 0.83–1.95 | |||||
BMI | >25 | 1.64 | 0.036 | 1.22 | 0.47 | ||
≦25≦25 | 1.03–2.59 | 0.71–2.07 | |||||
HR (ER/PgR) status | Positive | 1.49 | 0.062 | 1.25 | 0.37 | ||
Negative | 0.98–2.28 | 0.77–2.03 | |||||
HER2 status | Negative | 1.60 | 0.067 | 1.32 | 0.30 | ||
Positive | 0.97–2.65 | 0.77–2.26 | |||||
Liver metastasis | No | 0.95 | 0.067 | 0.93 | 0.72 | ||
Yes | 0.65–1.38 | 0.63–1.38 | |||||
Overall survival | |||||||
EILD | Yes | 2.22 | 0.038 | 1.75 | 0.17 | ||
No | 1.05–4.71 | 0.78–3.91 | |||||
Age | ≦56≦56 | 0.81 | 0.45 | 0.77 | 0.37 | ||
>56 | 0.47–1.39 | 0.43–1.36 | |||||
PS | 0 | 2.34 | 0.0021 | 2.37 | 0.0039 | ||
1,2 | 1.36–4.03 | 1.32–4.26 | |||||
Comorbid disease | Yes | 0.91 | 0.77 | 1.04 | 0.91 | ||
No | 0.49–1.70 | 0.51–2.13 | |||||
DFI | ≦2.8≦2.8 | 1.78 | 0.038 | 1.53 | 0.18 | ||
>2.8 | 1.03–3.07 | 0.83–2.85 | |||||
BMI | >25 | 1.33 | 0.39 | 1.13 | 0.75 | ||
≦25≦25 | 0.69–2.52 | 0.55–2.31 | |||||
HR (ER/PgR) status | Positive | 1.67 | 0.089 | 1.15 | 0.70 | ||
Negative | 0.93–3.01 | 0.57–2.29 | |||||
HER2 status | Negative | 1.87 | 0.093 | 1.42 | 0.39 | ||
Positive | 0.90–3.88 | 0.64–3.16 | |||||
Liver metastasis | No | 0.96 | 0.89 | 1.00 | 0.99 | ||
Yes | 0.56–1.64 | 0.56–1.79 |