Table 1 Correlation between the Foxp3 expression and clinicopathological characteristics of OSCC
From: Foxp3 overexpression in tumor cells predicts poor survival in oral squamous cell carcinoma
Clinical pathological feature | N | Expression of Foxp3 | |||
|---|---|---|---|---|---|
Stain value = 1 | Stain value = 2 | Stain value = 3 | P Value | ||
N = 99 | N = 106 | N = 68 | |||
Age | 0.65 | ||||
<60 | 133 | 51 (38.3 %) | 49 (36.9 %) | 33 (24.8 %) | |
≥60 | 140 | 48 (34.3 %) | 57 (40.7 %) | 35 (25.0 %) | |
Sex | 0.29 | ||||
Male | 188 | 63 (33.5 %) | 74 (39.4 %) | 51 (27.1 %) | |
Female | 85 | 36 (42.4 %) | 32 (37.6 %) | 17 (20.0 %) | |
Smoking | 0.84 | ||||
Yes | 132 | 47 (35.6 %) | 50 (37.9 %) | 35 (26.5 %) | |
No | 141 | 52 (36.9 %) | 56 (39.7 %) | 33 (23.4 %) | |
Drinking | 0.47 | ||||
Yes | 131 | 45 (34.4 %) | 49 (37.4 %) | 37 (28.2 %) | |
No | 142 | 54 (38.0 %) | 57 (40.1 %) | 31 (21.9 %) | |
Differentiation | 0.30 | ||||
High | 200 | 73 (36.5 %) | 82 (41.0 %) | 45 (22.5 %) | |
Medium | 64 | 23 (35.9 %) | 22 (34.4 %) | 19 (29.7 %) | |
Low | 9 | 3 (33.3 %) | 2 (22.2 %) | 4 (44.5 %) | |
Tumor site | 0.23 | ||||
Gingiva | 52 | 16 (30.8 %) | 19 (36.5 %) | 17 (32.7 %) | |
Tongue | 131 | 50 (38.1 %) | 47 (35.9 %) | 34 (26.0 %) | |
Buccal | 61 | 26 (42.6 %) | 24 (39.4 %) | 11 (18.0 %) | |
Othersa | 29 | 7 (24.1 %) | 16 (55.2 %) | 6 (20.7 %) | |
T stage | 0.63 | ||||
T1-T2 | 186 | 68 (36.5 %) | 74 (39.8 %) | 44 (23.7 %) | |
T3-T4 | 87 | 31 (35.6 %) | 32 (36.8 %) | 24 (27.6 %) | |
N stage | 0.000*** | ||||
N0 | 183 | 73 (39.9 %) | 82 (44.8 %) | 28 (15.3 %) | |
N1-N3 | 90 | 26 (28.9 %) | 24 (26.7 %) | 40 (44.4 %) | |
Clinical Stage | 0.09 | ||||
I-II | 142 | 55 (38.8 %) | 59 (41.5 %) | 28 (19.7 %) | |
III-IV | 131 | 44 (33.6 %) | 47 (35.9 %) | 40 (30.5 %) | |