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Table 1 Correlation between the Foxp3 expression and clinicopathological characteristics of OSCC

From: Foxp3 overexpression in tumor cells predicts poor survival in oral squamous cell carcinoma

Clinical pathological feature N Expression of Foxp3  
Stain value = 1 Stain value = 2 Stain value = 3 P Value
N = 99 N = 106 N = 68
Age      0.65
 <60 133 51 (38.3 %) 49 (36.9 %) 33 (24.8 %)  
 ≥60 140 48 (34.3 %) 57 (40.7 %) 35 (25.0 %)  
Sex      0.29
 Male 188 63 (33.5 %) 74 (39.4 %) 51 (27.1 %)  
 Female 85 36 (42.4 %) 32 (37.6 %) 17 (20.0 %)  
Smoking      0.84
 Yes 132 47 (35.6 %) 50 (37.9 %) 35 (26.5 %)  
 No 141 52 (36.9 %) 56 (39.7 %) 33 (23.4 %)  
Drinking      0.47
 Yes 131 45 (34.4 %) 49 (37.4 %) 37 (28.2 %)  
 No 142 54 (38.0 %) 57 (40.1 %) 31 (21.9 %)  
Differentiation      0.30
 High 200 73 (36.5 %) 82 (41.0 %) 45 (22.5 %)  
 Medium 64 23 (35.9 %) 22 (34.4 %) 19 (29.7 %)  
 Low 9 3 (33.3 %) 2 (22.2 %) 4 (44.5 %)  
Tumor site      0.23
 Gingiva 52 16 (30.8 %) 19 (36.5 %) 17 (32.7 %)  
 Tongue 131 50 (38.1 %) 47 (35.9 %) 34 (26.0 %)  
 Buccal 61 26 (42.6 %) 24 (39.4 %) 11 (18.0 %)  
 Othersa 29 7 (24.1 %) 16 (55.2 %) 6 (20.7 %)  
T stage      0.63
 T1-T2 186 68 (36.5 %) 74 (39.8 %) 44 (23.7 %)  
 T3-T4 87 31 (35.6 %) 32 (36.8 %) 24 (27.6 %)  
N stage      0.000***
 N0 183 73 (39.9 %) 82 (44.8 %) 28 (15.3 %)  
 N1-N3 90 26 (28.9 %) 24 (26.7 %) 40 (44.4 %)  
Clinical Stage      0.09
 I-II 142 55 (38.8 %) 59 (41.5 %) 28 (19.7 %)  
 III-IV 131 44 (33.6 %) 47 (35.9 %) 40 (30.5 %)  
  1. Stain value = 1, low level of Foxp3 expression; Stain value = 2, medium level of Foxp3 expression; Stain value = 3, high levels of Foxp3 expression
  2. aOthers included include hard palate, oropharynx and lips
  3. P value was determined using the Linear-by-Linear Association test. *,P<0.05;**, P<0.01;***, P<0.001