Table 2 Examples of Frequent/Representative Non-standardized Terms according to CTCAE v3.0
From: Use and misuse of common terminology criteria for adverse events in cancer clinical trials
Category | Descriptors in the Articles | Correct Form or Comments | Frequency |
|---|---|---|---|
Blood and lymphatic | Anemia Neutropenia Thrombocytopenia | Hemoglobin Neutrophils Platelets | 133/146 147/151 104/134 |
Constitutional | Edema Thromboembolic events Fatigue; asthenia Deterioration in general physical condition | Should be Edema-limb or similar Not an AE term Should use fatigue; they are separate terms in CTCAE v4.0. Not an AE term | 54/67 69 14 19 |
Decreased appetite | 23/49 | ||
gastrointestinal | Pyrexia Yellow skin Nausea-vomiting Lacrimation Nasopharyngitis Paresthesia Azotemia | Should use anorexia Not an AE term Not an AE term Not an AE term Not an AE term Not an AE term Not an AE term | 16 11 21 29 8 18 14 |
Other | Thyroid disorders Neutropenic fever Glossodynia Dysphonia Abdominal distention Renal impairment Menopausal symptoms Skin exfoliation Jaundice Psychiatric disorders Epistaxis Mucosal inflammation | Not an AE term Not an AE term Not an AE term Not an AE term Not an AE term Not an AE term Not an AE term Not an AE term Not an AE term Not an AE term Not an AE term Not an AE term | 9 22 31 8 15 12 21 29 16 18 9 23 |