Fig. 4

Effect of CQ on cell cycle distribution in D2A1 FUCCI tumors. a Representative fluorescence images of frozen sections of mammary tumors used to quantify cancer cells in S/G2/M (green) or G1/G0 (red) phases. b Effect of radiation on cell cycle distribution plotted as radiation-enhancement ratio of red and green cells in percentage. c Quantification of Ki67 by immunohistochemistry on D2A1 tumor frozen sections. *P < 0.05, **P < 0.01. Error bars indicate SEM for n = 4 to 11 independent experiments for each group