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Fig. 1 | BMC Cancer

Fig. 1

From: Stimulation of triple negative breast cancer cell migration and metastases formation is prevented by chloroquine in a pre-irradiated mouse model

Fig. 1

Effect of CQ on breast cancer cell invasion and growth. a Conditioned media from irradiated 3T3 fibroblasts was added in the lower compartment of invasion chamber and used as chemoattractant for breast cancer cells added in the upper compartment. Treatment with 5 μM CQ completely blocked radiation-enhancement of invasion in TNBC cell lines. Invasiveness of the non-TBNC cell lines were not modified by the irradiated 3T3 fibroblasts. CTL; Control, IRR; Irradiated, CQ; Chloroquine b Effect of CQ at 0, 2.5 or 5 μM on breast cancer cell growth measured 24, 48 and 72 h post treatment. Error bars indicate SEM. The experiment was realized in triplicate and repeated 3 times

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