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Table 3 Association between antigen specific human polyomavirus (HPyV) antibody levels and incident lung cancer, adjusted for matching variables

From: Absence of an association of human polyomavirus and papillomavirus infection with lung cancer in China: a nested case–control study

  Mean Trend Testd
Antibody quartile lnMFIa aOR (95%CIb) P c OR (95%CIb) P c
MCVe VP1f     1.00 (0.92–1.09) 0.951
 1 5.03 Referent    
 2 8.50 0.67 (0.38–1.17) 0.163   
 3 9.74 0.80 (0.49–1.31) 0.372   
 4 12.57 0.90 (0.37–2.17) 0.810   
MCVe ST-Agg     0.97 (0.88–1.08) 0.623
 1 0.02 Referent    
 2 0.05 1.01 (0.58–1.76) 0.985   
 3 0.25 0.70 (0.40–1.22) 0.209   
 4 4.12 0.85 (0.48–1.48) 0.553   
KIVh VP1g     1.04 (0.92–1.17) 0.532
 1 6.92 Referent    
 2 8.65 1.07 (0.61–1.88) 0.821   
 3 9.32 1.64 (0.94–2.89) 0.089   
 4 10.81 1.44 (0.82–2.52) 0.206   
KIVh ST-Agg     0.99 (0.90–1.10) 0.878
 1 0.02 Referent    
 2 0.22 1 .00 (0.58–1.75) 0.991   
 3 3.00 0.72 (0.41–1.27) 0.260   
 4 4.43 1.13 (0.65–1.98) 0.652   
WUVi VP1g     1.20 (0.96–1.51) 0.112
 1 8.16 Referent    
 2 8.86 1.34 (0.77–2.36) 0.305   
 3 9.34 1.15 (0.65–2.01) 0.643   
 4 10.13 1.47 (0.84–2.58) 0.182   
WUVi ST-Agg     1.02 (0.91–1.14) 0.734
 1 0.02 Referent    
 2 0.07 0.95 (0.55–1.67) 0.871   
 3 2.40 0.83 (0.47–1.45) 0.522   
 4 4.04 1.02 (0.58–1.78) 0.951   
  1. a lnMFI = natural log transformed median fluorescence intensity
  2. b Nominal (uncorrected) 95 % confidence intervals
  3. c P-values are corrected for multiple comparisons using permutation tests
  4. d The trend tests estimate the odds ratio for a one unit increase in natural log transformed MFI, adjusted for matched variables
  5. e MCV = Merkel cell polyomavirus
  6. f VP1 = the primary structural protein of human polyomaviruses
  7. g ST-Ag = the small T-antigen of human polyomaviruses
  8. h KIV = KI polyomavirus
  9. i WUV = WU polyomavirus