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Table 3 Association between antigen specific human polyomavirus (HPyV) antibody levels and incident lung cancer, adjusted for matching variables

From: Absence of an association of human polyomavirus and papillomavirus infection with lung cancer in China: a nested case–control study

 

Mean

Trend Testd

Antibody quartile

lnMFIa

aOR (95%CIb)

P c

OR (95%CIb)

P c

MCVe VP1f

   

1.00 (0.92–1.09)

0.951

 1

5.03

Referent

   

 2

8.50

0.67 (0.38–1.17)

0.163

  

 3

9.74

0.80 (0.49–1.31)

0.372

  

 4

12.57

0.90 (0.37–2.17)

0.810

  

MCVe ST-Agg

   

0.97 (0.88–1.08)

0.623

 1

0.02

Referent

   

 2

0.05

1.01 (0.58–1.76)

0.985

  

 3

0.25

0.70 (0.40–1.22)

0.209

  

 4

4.12

0.85 (0.48–1.48)

0.553

  

KIVh VP1g

   

1.04 (0.92–1.17)

0.532

 1

6.92

Referent

   

 2

8.65

1.07 (0.61–1.88)

0.821

  

 3

9.32

1.64 (0.94–2.89)

0.089

  

 4

10.81

1.44 (0.82–2.52)

0.206

  

KIVh ST-Agg

   

0.99 (0.90–1.10)

0.878

 1

0.02

Referent

   

 2

0.22

1 .00 (0.58–1.75)

0.991

  

 3

3.00

0.72 (0.41–1.27)

0.260

  

 4

4.43

1.13 (0.65–1.98)

0.652

  

WUVi VP1g

   

1.20 (0.96–1.51)

0.112

 1

8.16

Referent

   

 2

8.86

1.34 (0.77–2.36)

0.305

  

 3

9.34

1.15 (0.65–2.01)

0.643

  

 4

10.13

1.47 (0.84–2.58)

0.182

  

WUVi ST-Agg

   

1.02 (0.91–1.14)

0.734

 1

0.02

Referent

   

 2

0.07

0.95 (0.55–1.67)

0.871

  

 3

2.40

0.83 (0.47–1.45)

0.522

  

 4

4.04

1.02 (0.58–1.78)

0.951

  
  1. a lnMFI = natural log transformed median fluorescence intensity
  2. b Nominal (uncorrected) 95 % confidence intervals
  3. c P-values are corrected for multiple comparisons using permutation tests
  4. d The trend tests estimate the odds ratio for a one unit increase in natural log transformed MFI, adjusted for matched variables
  5. e MCV = Merkel cell polyomavirus
  6. f VP1 = the primary structural protein of human polyomaviruses
  7. g ST-Ag = the small T-antigen of human polyomaviruses
  8. h KIV = KI polyomavirus
  9. i WUV = WU polyomavirus