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Table 2 Summary of the dinuclear platinum compound-induced cytotoxicity in HeLa cells

From: Characterisation of the DNA sequence specificity, cellular toxicity and cross-linking properties of novel bispyridine-based dinuclear platinum complexes

Compound

IC50 (μM)

Cisplatin

9.3 ± 0.2

1,8 platinum

>130

1,10 platinum

>80

1,12 platinum

>40

  1. The compounds are ordered vertically in the table alongside their corresponding IC50 values. These IC50 values represent the drug concentration, in μM, at which a cell viability of 50 % was obtained, and were determined from a non-linear regression analysis using GraphPad Prism software. Each IC50 value was determined from the average of three separate experiments
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BMC Cancer

ISSN: 1471-2407

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