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Table 2 Downregulated proteins

From: Protein expression changes induced in a malignant melanoma cell line by the curcumin analogue compound D6

Accession Gene symbol Protein fold-change treated/control FDR
P83731 RPL24 60S ribosomal protein L24 −4.14 0.00054
P61254 RPL26 60S ribosomal protein L26 −3.63 0.02751
P52272 HNRNPM Heterogeneous nuclear ribonucleoprotein M −3.24 0.00004
P18621 RPL17 60S ribosomal protein L17 −3.11 0.02499
O60506 SYNCRIP Heterogeneous nuclear ribonucleoprotein Q −2.89 0.04096
P62280 RPS11 40S ribosomal protein S11 −2.73 0.00944
P23284 PPIB Peptidyl-prolyl cis-trans isomerase B −2.41 0.02471
P16104 H2AFX Histone H2AX −2.36 0.00054
P13667 PDIA4 Protein disulfide-isomerase A4 −2.05 0.04384
P16104 H2AFZ Histone H2A.Z −1.99 0.00109
Q93077 HIST1H2AC Histone H2A type 1-C −1.92 0.00096
P04908 HIST1H2AB Histone H2A type 1-B/E −1.77 0.00165
P20671 HIST1H2AD Histone H2A type 1-D −1.75 0.01570
Q92841 DDX17 Probable ATP-dependent RNA helicase DDX17 −1.63 0.00109
Q9UKM9 RALY RNA-binding protein Raly −1.47 0.00531
Q9Y6E2 BZW2 Basic leucine zipper and W2 domain-containing protein 2 −1.31 0.00531
  1. The table lists the proteins that showed to be downregulated (fold-change <−1.3) in LB24Dagi MM cells after 24 h of 10 μM D6 treatments (FDR <0.05). Proteins modulated also at the gene expression level are shown in bold characters [10]