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Fig. 1 | BMC Cancer

Fig. 1

From: Helicobacter pylori promotes angiogenesis depending on Wnt/beta-catenin-mediated vascular endothelial growth factor via the cyclooxygenase-2 pathway in gastric cancer

Fig. 1

Immunohistochemical assessment of COX-2, beta-catenin, and VEGF expression, and MVD in human gastric cancers. a COX-2 expression in H. pylori-negative gastric cancer tissues. b. COX-2 expression in H. pylori-positive gastric cancer tissues. c VEGF expression in H. pylori-negative gastric cancer tissues. d VEGF expression in H. pylori-positive gastric cancer tissues. e Beta-catenin expression in H. pylori-negative gastric cancer tissues. f. Beta-catenin expression in H. pylori-positive gastric cancer tissues. g MVD in H. pylori-negative gastric cancer tissues. h MVD in H. pylori-positive gastric cancer tissues. Red arrows indicate positive staining. Magnification, ×200. NOTE: Specimens were obtained from 106 patients who underwent major surgical resection for gastric cancer with no preoperative chemotherapy and radiotherapy between February 2009 and December 2014 at the Department of Surgery, Shuguang Hospital (affiliated with Shanghai University of Traditional Chinese Medicine, Shanghai, PR China)

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