Fig. 7

Effect of hemin and statins on GFP-K-Ras localization in PA-TU-8902 pancreatic cancer cells. The effect of a) vehicle, b) hemin (30 μM), c) cerivastatin (12 μM) and d) pravastatin (12 μM) on localization of GFP-K-Ras was tested in PA-TU-8902 pancreatic cancer cells transfected with pEGFP-K-RasWT plasmids after 24 h of treatment. CON, control cells; CER, cerivastatin; PRA, pravastatin