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Table 2 Multivariate analyses of progression-free and overall survival in 53 patients with ECOG PS 0-1

From: Combinatory effect of BRCA1 and HERC2 expression on outcome in advanced non-small-cell lung cancer

Progression-free survival

 

Hazard ratio

95 % CI

P-value

Performance status

   

 0

1.00 (referent)

  

 1

1.45

0.62-3.41

0.39

BRCA1/HERC2 expression

   

 Low/Low

1 (referent)

  

 Other combinations

1.45

1.10-4.73

0.03

Overall survival

 

Hazard ratio

95 % CI

P-value

Performance status

   

 0

1 (referent)

  

 1

1.35

0.45-4.1

0.58

BRCA1/HERC2 expression

   

 Low/Low

1 (referent)

  

 Other combinations

3.70

1.54 -9.10

0.004