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Table 5 Baseline characteristics of the RTC study participants

From: Alcohol-related breast cancer in postmenopausal women – effect of CYP19A1, PPARG and PPARGC1A polymorphisms on female sex-hormone levels and interaction with alcohol consumption and NSAID usage in a nested case-control study and a randomised controlled trial

Characteristic

PPARγ2 Pro12 (n = 18)

PPARγ2 12Ala (n = 7)

P-valuesd

Median

Range

Median

Range

Agea, years

58.5

(49–70)

55

(47–67)

0.28

Weight, kg

64.1

(50.1–86.5)

59.8

(57.2–68.4)

0.27

BMI, kg/m2

23.5

(19.1–26.9)

22.4

(19.4–24.5)

0.14

Years since last menses

5.5

(1–25)

6

(3–16)

0.46

Alcohol intake/week

6.5

(1–15)

6

(3.5–14)

0.70

Characteristic

PPARγ2 Pro12 (n = 18)

PPARγ2 12Ala (n = 7)

 

No.

%

No.

%

 

Menopause type

     

 Naturalb

17

94.4

6

85.7

 

 Hysterectomyc

1

6.6

1

14.3

 

Smoking status

     

 Never

10

55.6

5

71.4

 

 Former

8

44.4

2

28.6

 
  1. Characteristics of participants from the RCT divided by genotype
  2. aOne participant was only 48 years, but had not had her menses for 6 years. All other participants were older than 50 years
  3. bOne participant had had a unilateral oophorectomy
  4. cOne participant had a combined hysterectomy and oophorectomy; and one participant had a hysterectomy before last menses, but was older than 60 years
  5. dP-values for comparison of baseline characteristics using Student’s t-test