The occurrence of non-melanoma malignant skin lesions and non-cutaneous squamous-cell carcinoma among metastatic melanoma patients: an observational cohort study in Denmark

Table 1 Patient characteristics: comparison between those with (excluded) and without (included) prior history of cancer^a

	With a history of cancer		Without a history of cancer
	N	%	N	%
Total N	855	100.0	2814	100.0
Age (y) at diagnosis^b
Mean (SD)	67.9 (12.9)		63.3 (15.4)
Median (range)	69 (27–96)		64 (19–103)
Male	425	49.7	1540	54.7
Born in Denmark	836	97.8	2727	96.9
Site of metastasis^b
Skin	289	33.8	1527	54.3
Soft tissue	36	4.2	166	5.9
Liver	215	25.1	115	4.1
Lung	35	4.1	89	3.2
GI Tract	38	4.4	64	2.3
Brain	35	4.1	59	2.1
Bone	16	1.9	39	1.4
Salivary gland	12	1.4	34	1.2
Mamma	10	1.2	28	1.0
Cytology, pleura	4	0.5	17	0.6
Mucous membrane	6	0.7	6	0.2
Gallbladder/Pancreas	2	0.2	5	0.2
Vulva	4	0.5	5	0.2
Unspecified or unknown	153	17.9	660	23.5
Death^b	749	87.6	2093	74.4
Time (mo) to death^b, Median (range)	5.7 (0–156)		9.7 (0–176)

^aPatients were excluded if they had a history of cancer, other than melanoma, basal cell carcinoma, cutaneous squamous cell carcinoma, Bowen’s disease, actinic keratoses, and keratoacanthoma, before the metastatic melanoma diagnosis
^bP-value < 0.0001 for age at diagnosis (T-test), time to death (Wilcoxon rank sum test), number of death and site of metastasis (Chi-squared test)

ISSN: 1471-2407