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Table 1 Patient characteristics: comparison between those with (excluded) and without (included) prior history of cancera

From: The occurrence of non-melanoma malignant skin lesions and non-cutaneous squamous-cell carcinoma among metastatic melanoma patients: an observational cohort study in Denmark

  With a history of cancer Without a history of cancer
  N % N %
Total N 855 100.0 2814 100.0
Age (y) at diagnosisb   
 Mean (SD) 67.9 (12.9) 63.3 (15.4)
 Median (range) 69 (27–96) 64 (19–103)
Male 425 49.7 1540 54.7
Born in Denmark 836 97.8 2727 96.9
Site of metastasisb     
 Skin 289 33.8 1527 54.3
 Soft tissue 36 4.2 166 5.9
 Liver 215 25.1 115 4.1
 Lung 35 4.1 89 3.2
 GI Tract 38 4.4 64 2.3
 Brain 35 4.1 59 2.1
 Bone 16 1.9 39 1.4
 Salivary gland 12 1.4 34 1.2
 Mamma 10 1.2 28 1.0
 Cytology, pleura 4 0.5 17 0.6
 Mucous membrane 6 0.7 6 0.2
 Gallbladder/Pancreas 2 0.2 5 0.2
 Vulva 4 0.5 5 0.2
 Unspecified or unknown 153 17.9 660 23.5
Deathb 749 87.6 2093 74.4
 Time (mo) to deathb, Median (range) 5.7 (0–156) 9.7 (0–176)
  1. aPatients were excluded if they had a history of cancer, other than melanoma, basal cell carcinoma, cutaneous squamous cell carcinoma, Bowen’s disease, actinic keratoses, and keratoacanthoma, before the metastatic melanoma diagnosis
  2. bP-value < 0.0001 for age at diagnosis (T-test), time to death (Wilcoxon rank sum test), number of death and site of metastasis (Chi-squared test)