Table 2 Characteristics of patients with brain metastases in all studies
From: Systematic review: brain metastases from colorectal cancer—Incidence and patient characteristics
Article | Years | No. CRC patients | No. BM patients | Median age (years) | Median BMFI (month) | Male | Rectal primary | Extracranial metastases | Lung metastases | Liver metastases |
|---|---|---|---|---|---|---|---|---|---|---|
Characteristics of patients with brain metastases in studies including all patients diagnosed with colorectal cancer. | ||||||||||
ᅟNoura et al. [7] | 1985–2006 | 2299 | 29 | 61.1 (mean) | 34.3 | 79 % | 59 % | 79 % | 69 % | 24 % |
ᅟSuzuki et al. [8] | 1979–2010 | 5345 | 142 | 61 | 22.8 | 61 % | 43 % | 78 % | 66 % | 42 % |
ᅟHugen et al. [9] | 1991–2010 | 5817 | 54 | - | - | - | 41 % | - | - | - |
ᅟTan et al. [10] | 1995–2003 | 4378 | 27 | 66 | 27.5 | 52 % | 56 % | 93 % | 82 % | 51.9 % |
ᅟMongan et al. [11] | 1984–2006 | 1620 | 39 | - | 25 | 54 % | 43 % | 100 % | 78 % | |
ᅟJung et al. [12] | 1995–2008 | 8732 | 126 | - | 28.7 | 62 % | 63 % | 92.3 % | 72 % | 32.5 % |
ᅟPramateftakis et al. [13] | 1990–2009 | 670 | 5 | 55.7 | 7.5 (mean) | 80 % | 20 % | - | - | 80 % |
ᅟJiang et al. [14] | 1991–2010 | 8220 | 60 | 62.5 | 21 | 60 % | 50 % | 88 % | 65 % | 30 % |
ᅟTevlin et al. [15] | 1988–2012 | 4219 | 11 | 73 | 24 | 73 % | 27 % | 73 % | - | - |
ᅟTanriverdi et al. [16] | 2001–2012 | 4864 | 133 | - | 31 | 53 % | 56 % | 89 % | 65 % | 51 % |
ᅟTemple et al. [17] | 1959–1979 | 999 | 29 | - | - | 62 % | 41 % | - | 86 % | 76 % |
ᅟNaito et al. [18] | 1967–1992 | 778 | 15 | - | 22 | 53 % | 67 % | - | 80 % | - |
ᅟHammoud et al. [19] | 1980–1994 | 8632 | 150 | 61 | 26 | 62 % | 41 % | 95 % | 71 % | 52 % |
ᅟKo et al. [20] | 1970–1996 | 7153 | 53 | - | 33 | 74 % | 62 % | 77 % | 54 % | 26 % |
ᅟZorrilla et al. [21] | 1996–2000 | 378 | 53 | 61 | 30 | 44 % | 55 % | 100 % | 67 % | 67 % |
ᅟSchouten et al. [22] | 1986–1998 | 720 | 9 | - | - | - | - | - | - | - |
ᅟBarnholtz-Sloan et al. [23] | 1973–2001 | 42,817 | 779 | - | - | 53 % | - | - | - | - |
Characteristics of patients with brain metastases in studies including various selected cohorts of colorectal cancer patients. | ||||||||||
ᅟKim et al. [24] | 1987–2009 | 4350 | 38a | - | - | 66 % | 58 % | 5 % | - | - |
ᅟSundermeyer et al. [25] | 1993–2002 | 1020 | 33 | - | - | - | - | - | - | - |
ᅟYeager et al. [26] | 2008–2012 | 918 | 37 | - | - | - | - | - | - | - |
ᅟChyun et al. [27] | 1977–1989 | 78 | 18 | - | 28 | 50 % | - | 95 % | 55 % | 22 % |
ᅟPatanaphan et al. [28] | 1979–1982 | 163 | 4 | - | 33 | - | - | - | - | - |
ᅟTran et al. [29] | 1996–2009 | 524 | 27 | - | - | - | - | - | - | - |
ᅟHess et al. [30] | 1994–1997 | 984 | 7 | - | - | - | - | - | - | - |
ᅟTie et al. [31] | 1999–2009 | 46 | 46 | - | - | - | - | - | - | - |
ᅟKhattak et al. [32] | 2006–2011 | 2006 | 10 | - | - | - | - | - | - | - |
ᅟKemeny et al. [33] | 2003–2013 | 169 | 9 | - | - | - | - | - | - | - |
ᅟYoshidome et al. [34] | 1985–2001 | 207 | 8 | - | - | - | - | - | 75 % | - |
ᅟde Jong et al. [35] | 1982–2008 | 1669 | 22 | - | - | - | - | - | - | - |
ᅟByrne et al. [36] | 1987–2009 | 1304 | 52 | - | 40 | 56 % | - | 90 % | 81 % | 29 % |
ᅟHigashiyama et al. [37] | 1981–2001 | 100 | 13 | - | - | - | - | - | - | - |
ᅟHugen et al. second cohort [9] | 1996–1999 | 1530 | 17 | - | - | - | - | - | - | - |
ᅟChiang et al. [38] | 2002–2006 | 884 | - | - | - | - | - | - | - | |
ᅟWeiss et al. [39] | 1944–1984 | 1541 | 38 | - | - | - | - | - | 68 % | 74 % |
ᅟCascino et al. [40] | 1977–1980 | 1006 | 40 | 60 | 25 | 60 % | - | 98 % | 85 % | 50 % |
ᅟTakagawa et al. [41] | 1992–2003 | 638 | 8 | - | - | - | - | - | - | - |
ᅟvan Gestel et al. [42] | 2003–2008 | 5671 | 63 | - | - | - | - | 78 % | - | - |
ᅟTokoro et al. [43] | 1998–2010 | 1364 | 25 | - | 25 | 52 % | 48 % | 92 % | 92 % | 68 % |
ᅟScartozzi et al. [44] | 1995–2005 | 99 | 5 | - | - | - | - | - | - | - |
ᅟKruser et al. [45] | 1994–2005 | 49 | 49 | 66 | 23 | 67 % | 14 % | 82 % | 47 % | 33 % |
ᅟSmedby et al. [46] | 1987–2006 | 1001 | 1001 | - | 25 | - | - | - | - | - |
ᅟFokas et al. [47] | 1996–2007 | 78 | 78 | - | 20 | 39 % | - | 64 % | - | - |
ᅟMagni et al. [48] | 2003–2013 | 41 | 41 | 58 | 36 | 61 % | 59 % | 95 % | 88 % | 37 % |
ᅟFarnell et al. [49] | 1976–1993 | 150 | 150 | 65 | 23 | 58 % | 30 % | 81 % | 57 % | 29 % |
ᅟDamiens et al. [4] | 2000–2009 | 48 | 48 | 63 | 24 | 52 % | 48 % | 90 % | 64 % | 50 % |
ᅟKye et al. [50] | 1997–2006 | 39 | 39 | 59 | 32 (mean) | 59 % | 56 % | 97 % | 80 % | 41 % |
ᅟBeak et al. [51] | 2001–2009 | 118 | 118 | 58 | - | 53 % | 61 % | - | 75 % | 45 % |
ᅟNieder et al. [52] | 1983–2008 | 35 | 35 | - | - | - | - | - | - | - |
ᅟBartelt et al. [53] | 1985–2000 | 47 | 47 | - | 23 | - | 51 % | 100 % | 50 % | - |
ᅟHeisterkamp et al. [54] | 1989–2008 | 53 | 53 | - | - | 47 % | 36 % | 77 % | - | - |
ᅟMatsunaga et al. [55] | 1992–2008 | 152 | 152 | - | 27 | 67 % | 42 % | 74 % | 61 % | 33 % |
ᅟSchoeggl et al. [56] | 1993–1996 | 35 | 35 | - | 28 | 66 % | - | 63 % | 57 % | 46 % |
ᅟWronski et al. [57] | 1974–1993 | 73 | 73 | 61 | 28 | 41 % | 40 % | - | 74 % | 49 % |
ᅟFowler et al. [58] | 1999–2007 | 32 | 32 | 66 | 28 | 66 % | 31 % | - | 41 % | 44 % |
ᅟMaglio et al. [59] | 1999–2013 | 53 | 53 | 65 | - | 42 % | 43 % | 96 % | 75 % | - |
ᅟMege et al. [60] | 1998–2009 | 28 | 28 | 62 | - | 46 % | 46 % | - | 36 % | 29 % |
ᅟTaher et al. [61] | 1990–2009 | 37 | 37 | 63 | 35 | 54 % | - | - | - | - |
ᅟD’Andrea et al. [62] | 1960–2000 | 44 | 44 | 53 (mean) | 26 | 75 % | - | - | - | - |
ᅟSimonova et al. [63] | 1992–1998 | 30 | 30 | - | - | - | - | - | - | - |
ᅟOnodera et al. [64] | 1979–1998 | 1077 | 17 | - | - | 77 % | 71 % | 88 % | 76 % | 47 % |