Fig. 1
From: Epigenetic silencing of miR-181c by DNA methylation in glioblastoma cell lines
CTCF binds to the promoter of miR-181c. a IGV genome browser screenshot for ChIP-seq data of H3K4me3, H3K27ac, CTCF and Rad21 from K562 cells and Reduced Representation Bisulfite Sequencing (RRBS) data from the same cell line. Green bars, 0 % molecules sequenced are methylated; Yellow bars, 50 % molecules are methylated; Red bars, 100 % molecules sequenced are methylated. CTCF binding motif with the highest score is shown with reference to one CpG island. The region depicted is chr19:13,982,729-13,985,645. Data was downloaded from the Analysis/Data hub by the ENCODE project. b primiR-181c expression levels in different cells measured by RT-qPCR with SYBR Green. c miR-181c expression levels in different cells measured by Taqman assay