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Table 2 Association between overall ROH and TC (min. 75 SNPs per ROH)

From: Runs of homozygosity and inbreeding in thyroid cancer

 

Entire data set

  

Number of ROHa

Cases

Controls

OR

95 % CI

P

  < 10

204

152

1.00

Ref.

 

 10–12

145

88

1.22

0.87–1.72

0.23

 13–15

170

127

0.99

0.73–1.36

0.98

  > 15

130

64

1.55

1.05–2.18

0.02

Total length (Mb)

     

  < 14.1

153

117

1.00

Ref.

 

 14.1–19.4

156

114

1.04

0.74–1.47

0.79

 19.4–25.4

163

107

1.16

0.82–1.64

0.38

  > 25.4

177

93

1.45

1.02–2.06

0.03

  1. aCutoffs were chosen to produce approximately equal group sizes for cases and controls
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BMC Cancer

ISSN: 1471-2407

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