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Table 2 Association between overall ROH and TC (min. 75 SNPs per ROH)

From: Runs of homozygosity and inbreeding in thyroid cancer

  Entire data set   
Number of ROHa Cases Controls OR 95 % CI P
  < 10 204 152 1.00 Ref.  
 10–12 145 88 1.22 0.87–1.72 0.23
 13–15 170 127 0.99 0.73–1.36 0.98
  > 15 130 64 1.55 1.05–2.18 0.02
Total length (Mb)      
  < 14.1 153 117 1.00 Ref.  
 14.1–19.4 156 114 1.04 0.74–1.47 0.79
 19.4–25.4 163 107 1.16 0.82–1.64 0.38
  > 25.4 177 93 1.45 1.02–2.06 0.03
  1. aCutoffs were chosen to produce approximately equal group sizes for cases and controls