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Table 1 Hereditary tumors, histopathological features and cancer family history

From: Different Array CGH profiles within hereditary breast cancer tumors associated to BRCA1 expression and overall survival

Tumor ID Histological type Tumor grade IHC Mutation detected Family History
ER PR HER2 BRCA1 BRCA1 BRCA2
T6 IDC III - - - -    4 breast, 1 esophageal cancer
T10 IDC III - - - -    2 breast, 1 prostate cancer
T11 IDC III - - - -    1 breast bilateral with ovarian cancer
T12 IDC II - + - -    2 breast OR 1 breast, 1 ovarian, 1 stomach cancer
T17 IDC III - - - -    2 breast, 1 uterine, 1 testicular cancer
T20 LCIS _ - - 1+ -    3 breast, 1 stomach cancer
T24 IDC II - - - - YES   1 bilateral and 2 breast, 1 gallbladder cancer, 1 melanoma
T39 IDC III - - - -    1 bilateral and 3 breast cancer, 1 uterine, 1 stomach cancer
T41 IDC III - - - -    4 breast, 2 stomach,1 prostate cancer
T42 IDC III - - - -    4 breast, 2 stomach,1 prostate cancer
T43 IDC III - - - -    4 breast, 2 stomach,1 prostate cancer
T45 IDC II - + - -    1 bilateral breast, 4 breast, 1 testicular cancer
T25 IDC III + + - - YES   1 bilateral and 2 breast, 1 gallbladder cancer, 1 melanoma
T1 IDC III + - 1+ -    5 breast, 1 stomach, 1 gallbladder, 1 other cancer
T3 IDC III + + - -    2 breast, 1 uterine, 1 gallbladder, 1 esophageal cancer, 2 other cancer
T26 IDC III + + - -    6 breast, 1 stomach cancer, 1 leukemia
T29 IDC II + + 1+ -    5 breast, 1 liver, 2 stomach cancer
T32 IDC I + + - -    3 breast, 1 prostate, 1 uterine cancer
T35 IDC I + + - -    5 breast, 1 bilateral breast, 1 stomach, 1 pancreatic cancer
T36 IDC I + + - -    3 breast cancer
T37 IDC II + + - -    4 breast (1 bilateral), 1 testicular, 1 other cancer
T9 LCIS _ + + 3+ -    4 breast (1breast/colon), 3 stomach, 2 prostate, 1 pancreatic cancer
T15 IDC II + + 2+ -    3 breast cancer, one in a male
T21 ILC _ + + 2+ -    3 breast, 1 stomach, 1 other cancer
T4 IDC I - + - +    3 breast cancer
T5 IDC III - - - +   YES 2 breast, 1 stomach cancer, 1 leukemia
T16 IDC I - + - +    2 breast, 1 uterine, 1 stomach cancer
T23 IDC III - - - +    1 breast, 1 prostate OR 1 breast, 1 stomach, 1 other cancer
T19 LCIS _ - + 2+ +    3 breast, 1 stomach cancer
T46 IDC III - - 3+ +    1 bilateral and 1 breast cancer
T44 DCIS _ + + - +   YES 1 bilateral and 3 breast cancer, 1 ovarian cancer, 1 stomach, 1 other cancer
T49 IDC II + + - + YES   1 bilateral breast, 1 uterine cancer(abuela paterna)
T2 DCIS _ + + - +    2 breast, 1 liver cancer
T8 ILC _ + - - +    1 bilateral breast cancer
T13 DCIS _ + + - +    3 breast, 1 uterine, 2 stomach cancer
T22 IDC II + + - +    2 breast, 2 ovarian, 1 lung cancer, 1 lymphoma
T28 DCIS _ + + 1+ +    3 breast cancer, 1 esophageal cancer
T30 ILC _ + + 1+ +    3 breast, 1 lymphoma
T31 IDC I + + - +    3 breast, 1 prostate, 1 uterine cancer
T33 IDC III + + - +    5 breast, 1 bilateral breast, 1 stomach, 1 pancreatic cancer
T34 IDC II + + - +    5 breast, 1 bilateral breast, 1 stomach, 1 pancreatic cancer
T38 LCIS _ + + - +    4 breast (1 bilateral), 1 testicular, 1 other cancer
T47 IDC II + + - +    2 breast, 1 prostate OR 2 breast, 1 stomach cancer
T48 IDC III + - - +    3 breast cancer
T14 DCIS _ + + 2+ +    5 breast cancer
T51 IDC II + + ND ND   YES 2 breast, 1 stomach cancer, 1 colon cancer, 1 myeloma
T50 IDC III + - 1+ ND   YES 2 breast, 1 stomach cancer
  1. IDC Invasive Ductal Carcinoma, ILC Invasive Lobular Carcinoma, DCIS Ductal Carcinoma in situ, LCIS Lobular Carcinoma in situ
  2. ND Not determined