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Table 1 Hereditary tumors, histopathological features and cancer family history

From: Different Array CGH profiles within hereditary breast cancer tumors associated to BRCA1 expression and overall survival

Tumor ID

Histological type

Tumor grade

IHC

Mutation detected

Family History

ER

PR

HER2

BRCA1

BRCA1

BRCA2

T6

IDC

III

-

-

-

-

  

4 breast, 1 esophageal cancer

T10

IDC

III

-

-

-

-

  

2 breast, 1 prostate cancer

T11

IDC

III

-

-

-

-

  

1 breast bilateral with ovarian cancer

T12

IDC

II

-

+

-

-

  

2 breast OR 1 breast, 1 ovarian, 1 stomach cancer

T17

IDC

III

-

-

-

-

  

2 breast, 1 uterine, 1 testicular cancer

T20

LCIS

_

-

-

1+

-

  

3 breast, 1 stomach cancer

T24

IDC

II

-

-

-

-

YES

 

1 bilateral and 2 breast, 1 gallbladder cancer, 1 melanoma

T39

IDC

III

-

-

-

-

  

1 bilateral and 3 breast cancer, 1 uterine, 1 stomach cancer

T41

IDC

III

-

-

-

-

  

4 breast, 2 stomach,1 prostate cancer

T42

IDC

III

-

-

-

-

  

4 breast, 2 stomach,1 prostate cancer

T43

IDC

III

-

-

-

-

  

4 breast, 2 stomach,1 prostate cancer

T45

IDC

II

-

+

-

-

  

1 bilateral breast, 4 breast, 1 testicular cancer

T25

IDC

III

+

+

-

-

YES

 

1 bilateral and 2 breast, 1 gallbladder cancer, 1 melanoma

T1

IDC

III

+

-

1+

-

  

5 breast, 1 stomach, 1 gallbladder, 1 other cancer

T3

IDC

III

+

+

-

-

  

2 breast, 1 uterine, 1 gallbladder, 1 esophageal cancer, 2 other cancer

T26

IDC

III

+

+

-

-

  

6 breast, 1 stomach cancer, 1 leukemia

T29

IDC

II

+

+

1+

-

  

5 breast, 1 liver, 2 stomach cancer

T32

IDC

I

+

+

-

-

  

3 breast, 1 prostate, 1 uterine cancer

T35

IDC

I

+

+

-

-

  

5 breast, 1 bilateral breast, 1 stomach, 1 pancreatic cancer

T36

IDC

I

+

+

-

-

  

3 breast cancer

T37

IDC

II

+

+

-

-

  

4 breast (1 bilateral), 1 testicular, 1 other cancer

T9

LCIS

_

+

+

3+

-

  

4 breast (1breast/colon), 3 stomach, 2 prostate, 1 pancreatic cancer

T15

IDC

II

+

+

2+

-

  

3 breast cancer, one in a male

T21

ILC

_

+

+

2+

-

  

3 breast, 1 stomach, 1 other cancer

T4

IDC

I

-

+

-

+

  

3 breast cancer

T5

IDC

III

-

-

-

+

 

YES

2 breast, 1 stomach cancer, 1 leukemia

T16

IDC

I

-

+

-

+

  

2 breast, 1 uterine, 1 stomach cancer

T23

IDC

III

-

-

-

+

  

1 breast, 1 prostate OR 1 breast, 1 stomach, 1 other cancer

T19

LCIS

_

-

+

2+

+

  

3 breast, 1 stomach cancer

T46

IDC

III

-

-

3+

+

  

1 bilateral and 1 breast cancer

T44

DCIS

_

+

+

-

+

 

YES

1 bilateral and 3 breast cancer, 1 ovarian cancer, 1 stomach, 1 other cancer

T49

IDC

II

+

+

-

+

YES

 

1 bilateral breast, 1 uterine cancer(abuela paterna)

T2

DCIS

_

+

+

-

+

  

2 breast, 1 liver cancer

T8

ILC

_

+

-

-

+

  

1 bilateral breast cancer

T13

DCIS

_

+

+

-

+

  

3 breast, 1 uterine, 2 stomach cancer

T22

IDC

II

+

+

-

+

  

2 breast, 2 ovarian, 1 lung cancer, 1 lymphoma

T28

DCIS

_

+

+

1+

+

  

3 breast cancer, 1 esophageal cancer

T30

ILC

_

+

+

1+

+

  

3 breast, 1 lymphoma

T31

IDC

I

+

+

-

+

  

3 breast, 1 prostate, 1 uterine cancer

T33

IDC

III

+

+

-

+

  

5 breast, 1 bilateral breast, 1 stomach, 1 pancreatic cancer

T34

IDC

II

+

+

-

+

  

5 breast, 1 bilateral breast, 1 stomach, 1 pancreatic cancer

T38

LCIS

_

+

+

-

+

  

4 breast (1 bilateral), 1 testicular, 1 other cancer

T47

IDC

II

+

+

-

+

  

2 breast, 1 prostate OR 2 breast, 1 stomach cancer

T48

IDC

III

+

-

-

+

  

3 breast cancer

T14

DCIS

_

+

+

2+

+

  

5 breast cancer

T51

IDC

II

+

+

ND

ND

 

YES

2 breast, 1 stomach cancer, 1 colon cancer, 1 myeloma

T50

IDC

III

+

-

1+

ND

 

YES

2 breast, 1 stomach cancer

  1. IDC Invasive Ductal Carcinoma, ILC Invasive Lobular Carcinoma, DCIS Ductal Carcinoma in situ, LCIS Lobular Carcinoma in situ
  2. ND Not determined