Table 2 Protein expression for SFKs and downstream markers of activation and disease specific survival (n = 192)

Src Kinase

  Membrane

50 (27–80)

0.237

  Cytoplasmic

37 (27–68)

0.132

  Nucleus

2 (0–12)

0.726

SFK (Y416)

  Membrane

5 (0–13)

0.206

  Cytoplasmic

7 (0–20)

0.868

  Nucleus

2 (0–11)

0.735

FAK (Y861)

  Membrane

13 (3–37)

0.008

  Cytoplasmic

7 (0–20)

0.546

  Nuclear

60 (43–77)

0.532

FAK (Y397)

  Membrane

93 (41–147)

0.001

  Cytoplasmic

77 (33–133)

0.252

  Nuclear

152 (127–180)

0.846

Paxillin

  Membrane

3 (0–10)

0.050

  Cytoplasmic

7 (0–10)

0.335

  Nuclear

3 (0–63)

0.031

FYN

  Membrane

15 (2–30)

0.006

  Cytoplasmic

8 (2–17)

0.393

  Nuclear

13 (0–109)

0.139

LYN

  Membrane

37 (10–77)

0.141

  Cytoplasmic

70 (38–202)

0.446

  Nuclear

13 (0–109)

0.019

FGR

  Membrane

7 (0–22)

0.087

  Cytoplasmic

33 (15–60)

0.252

  Nuclear

9 (3–27)

0.503

HCK

  Membrane

63 (27–103)

0.038

  Cytoplasmic

47 (30–27)

0.109

  Nuclear

57 (30–80)

0.197

YES

  Membrane

47 (17–70)

0.0004

  Cytoplasm

38 (23–69)

0.271

  Nucleus

43 (27–62)

0.842