Copy number of the Adenomatous Polyposis Coli gene is not always neutral in sporadic colorectal cancers with loss of heterozygosity for the gene

Table 1 Clinical and molecular data for 38 colorectal adenocarcinomas with LOH of APC gene^a

Tumor type	No.	%
Cancer	36	94.7
Cancer with Residual adenoma	2	5.3
Gender
Male	20	52.6
Female	18	47.4
Location
Right	1	2.6
Cecum	4	10.5
Ascending	5	13.1
Transverse	3	7.9
Descending	4	10.5
Sigmoid	18	47.4
Rectum	2	5.3
Left	1	2.6
APC LOH ratio
Average	0.32
Range	0.12–0.49
KRAS
Mutated	16	42.1
Wild type	22	57.9
DCC
LOH	33	86.8
No LOH	3	7.9
Not done	2	5.3

ISSN: 1471-2407